Urinary fluoride output in children following the use of a dual-fluoride varnish formulation

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Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorAparício Carvalho Integrated Faculty-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorOlympio, Kelly Polido Kaneshiro-
Autor(es): dc.creatorDa Silva Cardoso, Vanessa Eid-
Autor(es): dc.creatorBorro Bijella, Maria Fernanda-
Autor(es): dc.creatorPessan, Juliano Pelim-
Autor(es): dc.creatorBotazzo Delbem, Alberto Carlos-
Autor(es): dc.creatorRabelo Buzalaf, Marília Afonso-
Data de aceite: dc.date.accessioned2025-08-21T17:00:48Z-
Data de disponibilização: dc.date.available2025-08-21T17:00:48Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2009-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S1678-77572009000300009-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/225532-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/225532-
Descrição: dc.descriptionobjective: This study evaluated the bioavailability of fluoride after topical application of a dual-fluoride varnish commercially available in Brazil, when compared to DuraphatTM. Material and methods: The urinary fluoride output was evaluated in seven 5- year-old children after application of the fluoride varnishes, in two different phases. In the first phase (I), children received topical application of the fluoride varnish Duofluorid XII (2.92% fluorine, calcium fluoride + 2.71% fluorine, sodium fluoride, FGM TM). After 1-month interval (phase II), the same amount (0.2 mL) of the fluoride varnish Duraphat (2.26% fluorine, sodium fluoride, Colgate TM) was applied. Before each application all the volunteers brushed their teeth with placebo dentifrice for 7 days. Urinary collections were carried out 24 h prior up to 48 h after the applications. Fluoride intake from the diet was also estimated. Fluoride concentration in diet samples and urine was analyzed with the fluoride ion-specific electrode and a miniature calomel reference electrode coupled to a potentiometer. Data were tested by ANOVA and Tukey's post hoc test (p<0.05). Results: There were significant differences in the urinary fluoride output between phases I and II. The use of Duofluorid XII did not significantly increase the urinary fluoride output, when compared to baseline levels. The application of Duraphat caused a transitory increase in the urinary fluoride output, returning to baseline levels 48 h after its use. Conclusions: The tested varnish formulation, which has been shown to be effective in in vitro studies, also can be considered safe.-
Descrição: dc.descriptionDepartment of Environmental Health School of Public Health University of São Paulo, São Paulo, SP-
Descrição: dc.descriptionDepartment of Biochemistry Institute of Chemistry University of São Paulo, São Paulo, SP-
Descrição: dc.descriptionDepartment of Public Health and Pediatric Dentistry Aparício Carvalho Integrated Faculty, RO-
Descrição: dc.descriptionDepartment of Pediatric Dentistry Araçatuba Dental School São Paulo State University, Araçatuba, SP-
Descrição: dc.descriptionDepartment of Biological Sciences Bauru School of Dentistry University of São Paulo, Bauru, SP-
Descrição: dc.descriptionDepartamento De Ciências Biológicas Faculdade de Odontologia De Bauru Universidade de São Paulo, Al. Octávio Pinheiro Brisolla, 9-75, Vila Universitária - 17012-901 - Bauru-SP-
Descrição: dc.descriptionDepartment of Pediatric Dentistry Araçatuba Dental School São Paulo State University, Araçatuba, SP-
Formato: dc.format179-183-
Idioma: dc.languageen-
Relação: dc.relationJournal of Applied Oral Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectChildren-
Palavras-chave: dc.subjectFluorine-
Palavras-chave: dc.subjectUrine. Toxicity-
Palavras-chave: dc.subjectVarnishes-
Título: dc.titleUrinary fluoride output in children following the use of a dual-fluoride varnish formulation-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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