Lack of association between ABO histo-blood groups, secretor and non-secretor phenotypes, and anti-Toxoplasma gondii antibodies among pregnant women from the northwestern region of São Paulo State, Brazil

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFaculty of Medicine of São Jose do Rio Preto (FAMERP)-
Autor(es): dc.contributorRegional Blood Bank-
Autor(es): dc.creatorBrandao de Mattos, Cinara C.-
Autor(es): dc.creatorCintra, Juliana R.-
Autor(es): dc.creatorFerreira, Ana I.C.-
Autor(es): dc.creatorSpegiorin, Ligia C.J.F.-
Autor(es): dc.creatorGalisteu, Katia J.-
Autor(es): dc.creatorMachado, Ricardo L.D.-
Autor(es): dc.creatorde Mattos, Luiz Carlos-
Data de aceite: dc.date.accessioned2025-08-21T15:49:54Z-
Data de disponibilização: dc.date.available2025-08-21T15:49:54Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2008-12-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/225395-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/225395-
Descrição: dc.descriptionIntroduction: Toxoplasma gondii infects humans in several manners including by the gastrointestinal tract where a-2-L-fucosyltransferase (FUTII) coded by the FUT2 gene (19q13.3) controls the expression of the ABH glycoconjugate profile. The presence of functional FUTII defines the secretor phenotype which is associated with ABO erythrocytic phenotypes. Due to the epidemiological and clinical importance of T. gondii infection, the aim of this work was to test the hypothesis that the ABH glycoconjugate profile expressed in the gastrointestinal tract is associated with the presence of antibodies against this parasite. Material and methods: A total of 367 pregnant women from the High-Risk Pregnancy Clinic of the University Hospital de Base in São José do Rio Preto were enrolled in this study. Two blood samples were drawn with only one being mixed with anticoagulant. ABO erythrocytic phenotyping and detection of anti-T. gondii antibodies were achieved by the haemagglutination test. Identification of the secretor status used the PCR-RFLP method. Results: Differences in the ABO erythrocytic phenotypes (P=0.20) and secretor and nonsecretor phenotypes (P=0.41), either in isolation or in association, were not statistically significant with respect to the presence or absence of anti-T. gondii antibodies. Conclusions: These results suggest that the ABH glycoconjugate profile expressed in the gastrointestinal tract under regulation of the FUT2 gene is not associated with anti-T. gondii antibodies. Copyright © 2008 Termedia & Banach.-
Descrição: dc.descriptionBiology Department IBILCE São Paulo State University (UNESP), São José do Rio, São Paulo State-
Descrição: dc.descriptionImmunogenetics Laboratory Molecular Biology Department Faculty of Medicine of São Jose do Rio Preto (FAMERP), Avenida Brigadeiro Faria Lima, 5416, 15090-000 - São José do Rio-
Descrição: dc.descriptionRegional Blood Bank, São Jose do Rio Preto, São Paulo State-
Descrição: dc.descriptionGynaecology and Obstetrics Department Faculty of Medicine of São Jose do Rio Preto (FAMERP), São Jose do Rio Preto, São Paulo State-
Descrição: dc.descriptionMicro-organism Investigation Centre Department of Dermatology Infectious and Parasitic Diseases Faculty of Medicine of São Jose do Rio Preto (FAMERP), São Jose do Rio Preto, São Paulo State-
Descrição: dc.descriptionBiology Department IBILCE São Paulo State University (UNESP), São José do Rio, São Paulo State-
Formato: dc.format254-258-
Idioma: dc.languageen-
Relação: dc.relationArchives of Medical Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectABO histo-blood groups-
Palavras-chave: dc.subjectFUT2 G428A-
Palavras-chave: dc.subjectFUT2 gene-
Palavras-chave: dc.subjectSecretor status-
Palavras-chave: dc.subjectToxoplasma gondii-
Título: dc.titleLack of association between ABO histo-blood groups, secretor and non-secretor phenotypes, and anti-Toxoplasma gondii antibodies among pregnant women from the northwestern region of São Paulo State, Brazil-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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