Anti-coagulase-negative Staphylococcus activity of ethanolic extracts of propolis from two Brazilian regions and synergism with antimicrobial drugs by the E-test method

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorInstituto de Biociências-
Autor(es): dc.creatorMantovani, R. P.-
Autor(es): dc.creatorRall, V. L.M.-
Autor(es): dc.creatorBatalha, J. E.N.-
Autor(es): dc.creatorFernandes, A. A.H.-
Autor(es): dc.creatorFernandes Jr., Ary-
Data de aceite: dc.date.accessioned2025-08-21T16:03:53Z-
Data de disponibilização: dc.date.available2025-08-21T16:03:53Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2008-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S1678-91992008000200012-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/225184-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/225184-
Descrição: dc.descriptionPropolis is a natural resinous substance collected by bees from vegetal sources and its therapeutic properties have been investigated. In this work, we evaluated the inhibitory activity of ethanolic extracts of propolis (EEP) from the Southeast and South of Brazil on coagulase-negative Staphylococcus (CNS) growth as well as the EEP in vitro synergism with antimicrobial drugs by using the diffusion method (E-test). The EEP chemical characteristics (dry weight, pH, flavonoid and phenolic compounds) were determined. Seven drugs were tested, and synergism was observed between three drugs and Southeast EEP, six drugs and South EEP, and one drug and ethanol control. Ethanolic extracts of propolis from the South of Brazil presented the greatest flavonoid content and synergism rate, while EEP from the Southeast presented the greatest anti-CNS activity and phenolic compound content. Results showed the correlation among anti-CNS activity, synergism rate and chemical characteristics of propolis.-
Descrição: dc.descriptionDepartment of Microbiology and Immunology Botucatu Institute of Biosciences São Paulo State University, Botucatu, São Paulo State-
Descrição: dc.descriptionDepartment of Chemistry and Biochemistry IBB UNESP, Botucatu, São Paulo State-
Descrição: dc.descriptionDepartamento de Microbiologia e Imunologia Instituto de Biociências Campus de Botucatu, SP-
Descrição: dc.descriptionDepartment of Microbiology and Immunology Botucatu Institute of Biosciences São Paulo State University, Botucatu, São Paulo State-
Descrição: dc.descriptionDepartment of Chemistry and Biochemistry IBB UNESP, Botucatu, São Paulo State-
Formato: dc.format357-365-
Idioma: dc.languageen-
Relação: dc.relationJournal of Venomous Animals and Toxins Including Tropical Diseases-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAntimicrobial drugs-
Palavras-chave: dc.subjectBrazilian propolis-
Palavras-chave: dc.subjectCoagulase-negative Staphylococcus-
Palavras-chave: dc.subjectE-test-
Palavras-chave: dc.subjectSynergism-
Título: dc.titleAnti-coagulase-negative Staphylococcus activity of ethanolic extracts of propolis from two Brazilian regions and synergism with antimicrobial drugs by the E-test method-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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