Occurrence of pneumocystis pneumonia in HIV-infected patients and the interference of the highly active antiretroviral therapy

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorBarbosa, Alexandre Naime-
Autor(es): dc.creatorSouza, L. R.-
Data de aceite: dc.date.accessioned2025-08-21T21:39:17Z-
Data de disponibilização: dc.date.available2025-08-21T21:39:17Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2008-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S1678-91992008000100012-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/225100-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/225100-
Descrição: dc.descriptionFrom the beginning of the AIDS epidemic, pneumocystis pneumonia (PCP) has been distinguished as one of the most frequent opportunistic diseases with high morbid-mortality. As from 1996, the advent of the highly active antiretroviral therapy (HAART) has changed the characteristics of such epidemic by reducing its related diseases and, as a result, AIDS-related mortality. With the purpose to estimate PCP occurrence and HAART interference, 376 HIV-infected or AIDS patients were studied from January 1992 to December 2002. Among them, 58 (15.5%) PCP cases were found. There was a higher occurrence of PCP in the group of patients in which HAART was not used, with 40 (69.0%) of the episodes. As regards the studied period, a tendency to a linear reduction in annual PCP incidence was observed. The mean of T CD4+ lymphocytes in the patients with PCP (117 cells/mm3) was significantly lower when compared to that of the other individuals (325 cells/mm3). Therefore, this study suggests a temporal reduction in PCP occurrence related to HAART use with higher T CD4+ lymphocyte counts. Nevertheless, this opportunistic infection still shows significant incidence in AIDS patients. (NCT00516581).-
Descrição: dc.descriptionDepartment of Tropical Diseases and Imaging Diagnosis Botucatu Medical School São Paulo State University - UNESP, Botucatu, São Paulo State-
Descrição: dc.descriptionDepartamento de Doenças Tropicais e Diagnóstico Por Imagem Faculdade de Medicina de Botucatu - UNESP, 18618-970, Botucatu, SP-
Descrição: dc.descriptionDepartment of Tropical Diseases and Imaging Diagnosis Botucatu Medical School São Paulo State University - UNESP, Botucatu, São Paulo State-
Descrição: dc.descriptionDepartamento de Doenças Tropicais e Diagnóstico Por Imagem Faculdade de Medicina de Botucatu - UNESP, 18618-970, Botucatu, SP-
Formato: dc.format152-160-
Idioma: dc.languageen-
Relação: dc.relationJournal of Venomous Animals and Toxins Including Tropical Diseases-
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Palavras-chave: dc.subjectAIDS-
Palavras-chave: dc.subjectAntiretroviral treatment-
Palavras-chave: dc.subjectPneumocystis pneumonia-
Palavras-chave: dc.subjectT CD4 + lymphocytes-
Título: dc.titleOccurrence of pneumocystis pneumonia in HIV-infected patients and the interference of the highly active antiretroviral therapy-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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