Efeitos do betacaroteno e do tabagismo sobre a remodelação cardíaca pós-infarto do miocárdio

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorZornoff, Leonardo A. M.-
Autor(es): dc.creatorDuarte, Daniella R.-
Autor(es): dc.creatorMinicucci, Marcos F.-
Autor(es): dc.creatorAzevedo, Paula S.-
Autor(es): dc.creatorMatsubara, Beatriz B.-
Autor(es): dc.creatorMatsubara, Luiz S.-
Autor(es): dc.creatorCampana, Álvaro O.-
Autor(es): dc.creatorPaiva, Sergio A. R.-
Data de aceite: dc.date.accessioned2025-08-21T22:43:13Z-
Data de disponibilização: dc.date.available2025-08-21T22:43:13Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2007-09-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/225024-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/225024-
Descrição: dc.descriptionObjective: To analyze the effects of beta-carotene on the ventricular remodeling process following myocardial infarction (MI) in rats exposed to cigarette smoke. Methods: After acute myocardial infarction (AMI), the animals were divided into four groups: 1) Group C, 24 animals that were given standard diet; 2) Group BC, 26 animals that were given beta-carotene; 3) Group ECS, 26 animals that were given standard diet and were exposed to cigarette smoke; and 4) Group BC+ECS, 20 animals that were given beta-carotene and were exposed to cigarette smoke. After six months, a morphofunctional study was performed. We used a 5% significance level. Results: As regards diastolic areas (DA) and systolic areas (SA), the values for the BC group were higher than those for the C group. If DA/body weight (BW) and SA/BW are considered, the values for group BC+ECS were higher than the values for group C. As regards the fractional area change, we observed significant differences between ECS (lower values) and C (higher values) and between BC (lower values) and C (higher values). Differences between groups regarding infarction size were not observed. The ECS group presented higher values for myocyte cross-section area (MCA) than control animals. Additionally, the BC+ECS group presented higher MCA values than the BC, ECS and C groups. Conclusion: After myocardial infarction, smoking and beta-carotene intensified the heart remodeling process; harmful effects of the remodeling process were heightened when the two treatments were used in conjunction.-
Descrição: dc.descriptionFaculdade de Medicina de Botucatu Universidade Estadual de São Paulo, Botucatu, SP-
Descrição: dc.descriptionFaculdade de Medicina de Botucatu Departamento de Clínica Médica, 18618-000 - Botucatu, SP-
Descrição: dc.descriptionFaculdade de Medicina de Botucatu Universidade Estadual de São Paulo, Botucatu, SP-
Descrição: dc.descriptionFaculdade de Medicina de Botucatu Departamento de Clínica Médica, 18618-000 - Botucatu, SP-
Formato: dc.format151-157-
Idioma: dc.languagept_BR-
Idioma: dc.languageen-
Relação: dc.relationArquivos Brasileiros de Cardiologia-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBetacarotene-
Palavras-chave: dc.subjectMyocardial infarction-
Palavras-chave: dc.subjectSmoking-
Palavras-chave: dc.subjectVentricular remodeling-
Título: dc.titleEfeitos do betacaroteno e do tabagismo sobre a remodelação cardíaca pós-infarto do miocárdio-
Título: dc.titleEffects of beta-carotene and smoking on heart remodeling after myocardial infarction-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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