Role of lateral hypothalamus on fluid, electrolyte, and cardiovascular responses to activation of the MSA

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorHaibara, A. S.-
Autor(es): dc.creatorSaad, W. A.-
Autor(es): dc.creatorMenani, J. V.-
Autor(es): dc.creatorDe Arruda Camargo, L. A.-
Autor(es): dc.creatorRenzi, A.-
Data de aceite: dc.date.accessioned2025-08-21T17:51:25Z-
Data de disponibilização: dc.date.available2025-08-21T17:51:25Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued1994-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1152/ajpregu.1994.266.2.r496-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/223979-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/223979-
Descrição: dc.descriptionIn this study we investigated the influence of electrolytic lesion or of opioid agonist injections into the lateral hypothalamus (LH) on the dipsogenic, natriuretic, kaliuretic, antidiuretic, pressor, and bradycardic effects of cholinergic stimulation of the medial septal area (MSA) in rats. Sham- and LH-lesioned male Holtzman rats received a stainless steel cannula implanted into the LH. Other groups of rats had cannulas implanted simultaneously into the MSA and LH. Carbachol (2 nmol) injection into the MSA induced water intake, pressor, and bradycardic responses. LH lesion reduced all of these effects (1-3 and 15-18 days). Previous injection of synthetic opiate agonist, FK-33824 (100 ng), into the LH reduced the water intake, natriuresis, kaliuresis, and pressor responses induced by carbachol injected into the MSA. These data show that both electrolytic lesion or injection of an opiate agonist in the LH reduces the fluid-electrolyte and cardiovascular responses to cholinergic activation of the MSA. The involvement of LH with central excitatory and inhibitory mechanisms related to fluid-electrolytic and cardiovascular control is suggested.-
Descrição: dc.descriptionDept. of Physiology School of Dentistry Paulista State University, Araraquara, SP 14801-903-
Descrição: dc.descriptionDept. of Physiology School of Dentistry Paulista State University, Araraquara, SP 14801-903-
Idioma: dc.languageen-
Relação: dc.relationAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectarterial pressure-
Palavras-chave: dc.subjectcardiovascular regulation-
Palavras-chave: dc.subjectcholinergic activation-
Palavras-chave: dc.subjectfluid and electrolyte balance-
Título: dc.titleRole of lateral hypothalamus on fluid, electrolyte, and cardiovascular responses to activation of the MSA-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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