The Proliferating Cell Nuclear Antigen Index in Breast Aarcinomas does not Correlate with Mitotic Index and Estrogen Receptor Immunoreactivity

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorSchmitt, F. C.-
Autor(es): dc.creatorPereira, E. M.-
Autor(es): dc.creatorAndrade, L. M.-
Autor(es): dc.creatorTorresan, M.-
Autor(es): dc.creatorde Lucca, L.-
Data de aceite: dc.date.accessioned2025-08-21T23:21:01Z-
Data de disponibilização: dc.date.available2025-08-21T23:21:01Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued1994-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/S0344-0338(11)80426-7-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/223972-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/223972-
Descrição: dc.descriptionTo investigate the expression of a marker of cell proliferation (PCNA/Cyclin) and itsputative relationship with bistological grading, mitotic index and estrogen receptor immunoreactivity, we studied twenty-seven cases of invasive breast carcinoma in formalin-fixed, paraffin-embedded tissue sections. The PCNA and estrogen receptor were detected by the PC10 and H 222 monoclonal antibodies respectively, using an avidin-biotin-peroxidase method. The median value of PCNA index was 20.9% with a range from 1.4 to 84.2%. We did not find any significant relationship between PCNA index and the bistological grading, mitotic index and estrogen receptor immunoreactivity. We conclude that PCNA detected by the monoclonal antibody PC 10 in formalin-fixed material looks at present unrealiable as a proliferation marker in breast carcinoma. © 1994, Gustav Fischer Verlag · Stuttgart · Jena · New York. All rights reserved.-
Descrição: dc.descriptionDepartments of Pathology and Gynecology and Obstetrics School ofMedicine UNESP, Botucatu, Sao Paulo-
Descrição: dc.descriptionDepartments of Pathology and Gynecology and Obstetrics School ofMedicine UNESP, Botucatu, Sao Paulo-
Formato: dc.format786-791-
Idioma: dc.languageen-
Relação: dc.relationPathology Research and Practice-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBreast cancer-
Palavras-chave: dc.subjectEstrogen receptor-
Palavras-chave: dc.subjectPC 10-
Palavras-chave: dc.subjectProliferative cell nuclear antigen-
Título: dc.titleThe Proliferating Cell Nuclear Antigen Index in Breast Aarcinomas does not Correlate with Mitotic Index and Estrogen Receptor Immunoreactivity-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.