Hypothalamic lesions increase saline ingestion induced by injection of angiotensin II into AV3V in rats

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorDe Arruda Camargo, L. A.-
Autor(es): dc.creatorSaad, W. A.-
Autor(es): dc.creatorRenzi, A.-
Autor(es): dc.creatorDe Luca, L. A.-
Autor(es): dc.creatorGoncalves, J. R.-
Autor(es): dc.creatorMenani, J. V.-
Data de aceite: dc.date.accessioned2025-08-21T17:31:29Z-
Data de disponibilização: dc.date.available2025-08-21T17:31:29Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued1991-01-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/223923-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/223923-
Descrição: dc.descriptionWater and 3% NaCl intake were increased by the injection of 4 ng angiotensin II (ANG II) into the anteroventral third ventricle (AV3V) region of rats. Pretreatment with two specific ANG II receptor antagonists, [octanoyl-Leu8]ANG II and [Leu8]ANG II, significantly reduced ANG II-induced water and saline intake. This inhibition lasted ~30 min, with partial recovery at 60 min. In rats with electrolytic lesion of the bilateral ventromedial nucleus of hypothalamus (VMH), the effect of ANG II on water intake was not different from that observed in sham rats, but saline ingestion increased. In summary, the present results show that the AV3V region is an important central structure for ANG II-induced saline ingestion. Lesion of the VMH increases the response to ANG II, showing an interaction between the AV3V region and the VMH in the regulation of salt ingestion.-
Descrição: dc.descriptionDept. of Physiology School of Dentistry Paulista State University, 1680 Humaita St., Araraquara, SP, 14800-
Descrição: dc.descriptionDept. of Physiology School of Dentistry Paulista State University, 1680 Humaita St., Araraquara, SP, 14800-
Idioma: dc.languageen-
Relação: dc.relationAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAngiotensin II antagonists-
Palavras-chave: dc.subjectSalt ingestion-
Palavras-chave: dc.subjectWater ingestion-
Título: dc.titleHypothalamic lesions increase saline ingestion induced by injection of angiotensin II into AV3V in rats-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.