Characterization of packed-bed in the downcomer of a concentric internal-loop airlift bioreactor

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorMazziero, Vítor Teixeira-
Autor(es): dc.creatorBatista, Vinícius Guerso-
Autor(es): dc.creatorOliveira, Daniele Gonçalves de-
Autor(es): dc.creatorScontri, Mateus-
Autor(es): dc.creatorde Paula, Ariela Veloso-
Autor(es): dc.creatorCerri, Marcel Otavio-
Data de aceite: dc.date.accessioned2025-08-21T20:49:09Z-
Data de disponibilização: dc.date.available2025-08-21T20:49:09Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.bej.2022.108407-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/223710-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/223710-
Descrição: dc.descriptionA packed-bed basket containing corn cob powder was used for the adaptation of a concentric-tube airlift reactor for enzymatic reactions. The bed was inserted in the downcomer region of the bioreactor generating a decrease in liquid downflow. To characterize the liquid velocity through the packed-bed and calculate the residence time, the intrinsic permeability was determined using Darcy's law, resulting in 1.275 × 10−9 m2 (40-mesh particle size), and the pressure difference was calculated using the riser gas holdup, reaching values up to 56.6% for water at 3.5 vvm. Thus, a superficial liquid velocity model was obtained to describe the liquid velocity at different airflow rates and bed lengths, covering a wide range of support masses commonly used in enzymatic reactions. The model also allows the variation of viscosity, caused by different reaction temperatures and the use of larger bed sizes for scaling. Using the dye tracer method, it was possible to visualize the flow through the bed and corroborate the residence times obtained by the model for a wide range of airflows. Therefore, it describes the use of a basket filled with potential enzyme support, contributing to the applicability of pneumatic systems as enzymatic bioreactors, particularly internal-loop airlift reactors.-
Descrição: dc.descriptionDepartment of Bioprocess Engineering and Biotechnology School of Pharmaceutical Sciences São Paulo State University, São Paulo-
Descrição: dc.descriptionDepartment of Bioprocess Engineering and Biotechnology School of Pharmaceutical Sciences São Paulo State University, São Paulo-
Idioma: dc.languageen-
Relação: dc.relationBiochemical Engineering Journal-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subject3D printed-
Palavras-chave: dc.subjectEnzymatic bioreactor-
Palavras-chave: dc.subjectGas holdup-
Palavras-chave: dc.subjectPacked-bed permeability-
Título: dc.titleCharacterization of packed-bed in the downcomer of a concentric internal-loop airlift bioreactor-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.