Comparison of GentleWave system and passive ultrasonic irrigation with minimally invasive and conventional instrumentation against LPS in infected root canals

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorSchool of Dentistry-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorVelardi, Johnathan P.-
Autor(es): dc.creatorAlquria, Theeb A.-
Autor(es): dc.creatorAlfirdous, Rayyan A.-
Autor(es): dc.creatorCorazza, Bruna J. M.-
Autor(es): dc.creatorGomes, Ana P. M.-
Autor(es): dc.creatorSilva, Eduardo G.-
Autor(es): dc.creatorGriffin, Ina L.-
Autor(es): dc.creatorTordik, Patricia A.-
Autor(es): dc.creatorMartinho, Frederico C.-
Data de aceite: dc.date.accessioned2025-08-21T21:07:42Z-
Data de disponibilização: dc.date.available2025-08-21T21:07:42Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1038/s41598-022-08835-4-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/223705-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/223705-
Descrição: dc.descriptionThis study compared the effectiveness of GentleWave system (GWS) and passive ultrasonic irrigation (PUI) in removing lipopolysaccharides (LPS) from infected root canals after minimally invasive (MIT) and conventional instrumentation (CIT) techniques. Sixty first premolars with two roots were inoculated with fluorescent LPS conjugate (Alexa Fluor 594). Of those, twelve were dentin pretreated, inoculated with fluorescent LPS conjugate, and submitted to confocal laser scanning microscopy (CLSM) to validate the LPS-infection model. Forty-eight teeth were randomly divided into treatment groups: GWS + MIT, GWS + CIT, PUI + MIT, and PUI + CIT (all, n = 12). Teeth were instrumented with Vortex Blue rotary file size 15/0.04 for MIT and 35/0.04 for CIT. Samples were collected before (s1) and after a root canal procedure (s2) and after cryogenically ground the teeth (s3) for intraradicular LPS analysis. LPS were quantified with LAL assay (KQCL test). GWS + MIT and GWS + CIT were the most effective protocols against LPS, with no difference between them (p > 0.05). PUI + CIT was more effective than PUI + MIT (p < 0.05) but less effective than GWS + MIT and GWS + CIT. GWS was the most effective protocol against LPS in infected root canals using MIT and CIT techniques.-
Descrição: dc.descriptionDivision of Endodontics Department of Advanced Oral Sciences and Therapeutics University of Maryland School of Dentistry-
Descrição: dc.descriptionDepartment of Restorative Dentistry Endodontic Division São Paulo State University (Unesp) Institute of Science and Technology-
Descrição: dc.descriptionDepartment of Social and Pediatric Dentistry Institute of Science and Technology São Paulo State University (Unesp) Institute of Science and Technology-
Descrição: dc.descriptionDepartment of Restorative Dentistry Endodontic Division São Paulo State University (Unesp) Institute of Science and Technology-
Descrição: dc.descriptionDepartment of Social and Pediatric Dentistry Institute of Science and Technology São Paulo State University (Unesp) Institute of Science and Technology-
Idioma: dc.languageen-
Relação: dc.relationScientific Reports-
???dc.source???: dc.sourceScopus-
Título: dc.titleComparison of GentleWave system and passive ultrasonic irrigation with minimally invasive and conventional instrumentation against LPS in infected root canals-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.