Ultrastructural and Molecular Development of the Myotendinous Junction Triggered by Stretching Prior to Resistance Exercise

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorJacob, Carolina Dos S.-
Autor(es): dc.creatorBarbosa, Gabriela K.-
Autor(es): dc.creatorRodrigues, Mariana P.-
Autor(es): dc.creatorPimentel Neto, Jurandyr-
Autor(es): dc.creatorRocha-Braga, Lara C.-
Autor(es): dc.creatorDe Oliveira, Camilla G.-
Autor(es): dc.creatorChacur, Marucia-
Autor(es): dc.creatorCiena, Adriano P.-
Data de aceite: dc.date.accessioned2025-08-21T18:23:42Z-
Data de disponibilização: dc.date.available2025-08-21T18:23:42Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1017/S1431927622000186-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/223678-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/223678-
Descrição: dc.descriptionThe myotendinous junction (MTJ) is a highly specialized region of the locomotor apparatus. Here, we investigated the ultrastructural and molecular effects in the MTJ region after static stretching prior to the ladder-based resistance training. Thirty-two male, 60-day old Wistar rats were divided into four groups: Sedentary, Resistance Training, Stretching, and Stretching-Resistance Training. The gastrocnemius muscle was processed for transmission electron microscopy techniques and Western blot assay. We observed that the static stretching prior to the ladder-based resistance training increased the MTJ components, the fibroblast growth factor (FGF)-2 and FGF-6 protein expression. Also, we demonstrated the lower transforming growth factor expression and no difference in the lysyl oxidase expression after combined training. The MTJ alterations in response to combined training demonstrate adaptive mechanisms which can be used for the prescription or development of methods to reduce or prevent injuries in humans and promote the myotendinous interface benefit.-
Descrição: dc.descriptionLaboratory of Morphology and Physical Activity (LAMAF) Institute of Biosciences São Paulo State University (UNESP), SP-
Descrição: dc.descriptionLaboratory of Functional Neuroanatomy of Pain (LAND) Department of Anatomy Universidade de Sao Paulo (USP), SP-
Descrição: dc.descriptionLaboratory of Morphology and Physical Activity (LAMAF) Institute of Biosciences São Paulo State University (UNESP), SP-
Idioma: dc.languageen-
Relação: dc.relationMicroscopy and Microanalysis-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectFGF-
Palavras-chave: dc.subjectmyotendinous interface-
Palavras-chave: dc.subjectresistance training-
Palavras-chave: dc.subjectsarcomere-
Palavras-chave: dc.subjectTGF-β1-
Título: dc.titleUltrastructural and Molecular Development of the Myotendinous Junction Triggered by Stretching Prior to Resistance Exercise-
Tipo de arquivo: dc.typelivro digital-
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