Myotendinous Junction: Exercise Protocols Can Positively Influence Their Development in Rats

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorNeto, Jurandyr Pimentel-
Autor(es): dc.creatorRocha-Braga, Lara Caetano-
Autor(es): dc.creatorDos Santos Jacob, Carolina-
Autor(es): dc.creatorTomiate, André Neri-
Autor(es): dc.creatorCiena, Adriano Polican-
Data de aceite: dc.date.accessioned2025-08-21T16:12:09Z-
Data de disponibilização: dc.date.available2025-08-21T16:12:09Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/biomedicines10020480-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/223543-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/223543-
Descrição: dc.descriptionThe myotendinous junction (MTJ) is an interface that different stimuli alter their morphol-ogy. One of the main stimuli to promote alterations in the MTJ morphology is physical exercise. The present study aimed to investigate the morphology and molecular MTJ adaptations of biceps brachii muscle in adult Wistar rats submitted to different ladder-based protocols. Forty Wistar rats (90 days old) were divided into four groups: Sedentary (S), Climbing (C), Overload Climbing (OC), Climbing, and Overload Climbing (COC). The results of light microscopy demonstrated the cell and collagen tissue reorganization in the experimental groups. The sarcomeres lengths of different regions showed a particular development according to the specific protocols. The sarcoplasmic invagina-tions and evaginations demonstrated positive increases that promoted the myotendinous interface development. In the extracellular matrix, the structures presented an increase principally in the COC group. Finally, the immunofluorescence analysis showed the telocytes disposition adjacent to the MTJ region in all experimental groups, revealing their network organization. Thus, we concluded that the different protocols contributed to the morphological adaptations with beneficial effects in distinct ways of tissue and cellular development and can be used as a model for MTJ remodeling to future proteomic and genetic analysis.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionLaboratory of Morphology and Physical Activity—LAMAF Institute of Biosciences—IB São Paulo State University—UNESP, 24A, No.1515, SP-
Descrição: dc.descriptionLaboratory of Morphology and Physical Activity—LAMAF Institute of Biosciences—IB São Paulo State University—UNESP, 24A, No.1515, SP-
Descrição: dc.descriptionFAPESP: #2018/09199-8-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2017/12525-1-
Descrição: dc.descriptionFAPESP: 2017/21977-3-
Idioma: dc.languageen-
Relação: dc.relationBiomedicines-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBasal lamina-
Palavras-chave: dc.subjectMorphometry-
Palavras-chave: dc.subjectMyotendinous junction-
Palavras-chave: dc.subjectTelocyte-
Título: dc.titleMyotendinous Junction: Exercise Protocols Can Positively Influence Their Development in Rats-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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