Genetic polymorphisms are not associated with energy intake 1 year after Roux-en-Y gastric bypass in women

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Metodista de Piracicaba-
Autor(es): dc.contributorPUC-Campinas-
Autor(es): dc.contributorClínica Bariátrica de Piracicaba-
Autor(es): dc.creatorNovais, Patrícia Fatima Sousa-
Autor(es): dc.creatorCrisp, Alex Harley-
Autor(es): dc.creatorLeandro-Merhi, Vania Aparecida-
Autor(es): dc.creatorCintra, Renata Maria Galvão-
Autor(es): dc.creatorRasera, Irineu-
Autor(es): dc.creatorOliveira, Maria Rita Marques de-
Data de aceite: dc.date.accessioned2025-08-21T18:11:57Z-
Data de disponibilização: dc.date.available2025-08-21T18:11:57Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/jhn.12984-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/223269-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/223269-
Descrição: dc.descriptionBackground: The present study aimed to investigate the influence of food intake on body weight loss (WL) and the association of gene polymorphisms, 1 year after Roux-en-Y gastric bypass (RYGB) surgery. Methods: In total, 95 obese women (age ranged 20–50 years) in a Brazilian cohort underwent RYGB surgery and completed the study. Anthropometric measurements and food intake were assessed before and 1 year after surgery. Twelve gene polymorphisms (GHRL rs26802; GHSR rs572169; LEP rs7799039; LEPR rs1137101; 5-HT2C rs3813929; UCP2 rs659366; UCP2 rs660339; UCP3 rs1800849; SH2B1 rs7498665; TAS1R2 rs35874116; TAS1R2 rs9701796; and FTO rs9939609) were determined using a real-time polymerase chain reaction and a TaqMan assay. The subjects were divided into quartiles regarding percentage of excess weight loss (%EWL). The effect of genetic variants on energy and macronutrient intake was evaluated by simple logistic regression, followed by multiple logistic regression. Results: Subjects in the first and second quartiles showed a higher initial body mass index. Energy and macronutrient intake before and 1 year after RYGB surgery did not differ between the %EWL quartiles. None of gene polymorphisms investigated showed an association with the estimated energy intake 1 year after surgery. Conclusions: In conclusion, the estimate energy and food intake did not predict a greater body WL 1 year after RYGB surgery. In addition, the 12 gene polymorphism investigated did not affect the energy intake among female patients.-
Descrição: dc.descriptionInstitute of Biosciences Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo-
Descrição: dc.descriptionHuman Performance Laboratory Universidade Metodista de Piracicaba, São Paulo-
Descrição: dc.descriptionPostgraduate Program in Health Sciences PUC-Campinas, São Paulo-
Descrição: dc.descriptionClínica Bariátrica de Piracicaba, São Paulo-
Descrição: dc.descriptionInstitute of Biosciences Universidade Estadual Paulista Júlio de Mesquita Filho, São Paulo-
Idioma: dc.languageen-
Relação: dc.relationJournal of Human Nutrition and Dietetics-
???dc.source???: dc.sourceScopus-
Título: dc.titleGenetic polymorphisms are not associated with energy intake 1 year after Roux-en-Y gastric bypass in women-
Tipo de arquivo: dc.typelivro digital-
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