Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorPontificia Universidad Católica de Chile-
Autor(es): dc.contributorUniversidad de Talca-
Autor(es): dc.contributorUniversidad de Antofagasta-
Autor(es): dc.contributorPontificia Universidad Javeriana-
Autor(es): dc.contributorUniversidad de Valparaíso-
Autor(es): dc.contributorHospital Zambrano-Hellion-
Autor(es): dc.contributorUniversidad de Sevilla-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Queensland-
Autor(es): dc.contributorUniversity Medical Center Groningen (UMCG)-
Autor(es): dc.contributorUniversity Medical Center Groningen-
Autor(es): dc.contributorNestlé Institute for Health Sciences-
Autor(es): dc.creatorValero, Paola-
Autor(es): dc.creatorFuentes, Gonzalo-
Autor(es): dc.creatorCornejo, Marcelo-
Autor(es): dc.creatorVega, Sofía [UNESP]-
Autor(es): dc.creatorGrismaldo, Adriana-
Autor(es): dc.creatorPardo, Fabián-
Autor(es): dc.creatorGarcía-Rivas, Gerardo-
Autor(es): dc.creatorHillebrands, Jan-Luuk-
Autor(es): dc.creatorFaas, Marijke M.-
Autor(es): dc.creatorCasanello, Paola-
Autor(es): dc.creatorvan der Beek, Eline M.-
Autor(es): dc.creatorvan Goor, Harry-
Autor(es): dc.creatorSobrevia, Luis [UNESP]-
Data de aceite: dc.date.accessioned2022-08-04T22:12:13Z-
Data de disponibilização: dc.date.available2022-08-04T22:12:13Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.mam.2021.101019-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/222349-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/222349-
Descrição: dc.descriptionA balanced communication between the mother, placenta and foetus is crucial to reach a successful pregnancy. Several windows of exposure to environmental toxins are present during pregnancy. When the women metabolic status is affected by a disease or environmental toxin, the foetus is impacted and may result in altered development and growth. Gestational diabetes mellitus (GDM) is a disease of pregnancy characterised by abnormal glucose metabolism affecting the mother and foetus. This disease of pregnancy associates with postnatal consequences for the child and the mother. The whole endogenous and exogenous environmental factors is defined as the exposome. Endogenous insults conform to the endo-exposome, and disruptors contained in the immediate environment are the ecto-exposome. Some components of the endo-exposome, such as Selenium, vitamins D and B12, adenosine, and a high-fat diet, and ecto-exposome, such as the heavy metals Arsenic, Mercury, Lead and Copper, and per- and polyfluoroakyl substances, result in adverse pregnancies, including an elevated risk of GDM or gestational diabesity. The impact of the exposome on the human placenta's vascular physiology and function in GDM and gestational diabesity is reviewed.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionRijksuniversiteit Groningen-
Descrição: dc.descriptionUniversidade Estadual Paulista-
Descrição: dc.descriptionPontificia Universidad Javeriana-
Descrição: dc.descriptionFondo Nacional de Desarrollo Científico y Tecnológico-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionCellular and Molecular Physiology Laboratory (CMPL) Department of Obstetrics Division of Obstetrics and Gynaecology School of Medicine Faculty of Medicine Pontificia Universidad Católica de Chile-
Descrição: dc.descriptionFaculty of Health Sciences Universidad de Talca-
Descrição: dc.descriptionFaculty of Health Sciences Universidad de Antofagasta-
Descrição: dc.descriptionDepartment of Nutrition and Biochemistry Faculty of Sciences Pontificia Universidad Javeriana-
Descrição: dc.descriptionMetabolic Diseases Research Laboratory Interdisciplinary Centre of Territorial Health Research (CIISTe) Biomedical Research Center (CIB) San Felipe Campus School of Medicine Faculty of Medicine Universidad de Valparaíso-
Descrição: dc.descriptionTecnologico de Monterrey Escuela de Medicina y Ciencias de la Salud Cátedra de Cardiología Hospital Zambrano-Hellion, TecSalud, San Pedro Garza-García-
Descrição: dc.descriptionDepartment of Obstetrics Division of Obstetrics and Gynaecology and Department of Neonatology Division of Pediatrics School of Medicine Faculty of Medicine Pontificia Universidad Católica de Chile-
Descrição: dc.descriptionDepartment of Physiology Faculty of Pharmacy Universidad de Sevilla-
Descrição: dc.descriptionMedical School (Faculty of Medicine) Sao Paulo State University (UNESP)-
Descrição: dc.descriptionUniversity of Queensland Centre for Clinical Research (UQCCR) Faculty of Medicine and Biomedical Sciences University of Queensland-
Descrição: dc.descriptionDepartment of Obstetrics and Gynaecology University of Groningen University Medical Center Groningen (UMCG), Hanzeplein 1, Groningen-
Descrição: dc.descriptionDepartment of Pediatrics University of Groningen University Medical Center Groningen-
Descrição: dc.descriptionNestlé Institute for Health Sciences, Nestlé Research, Societé des Produits de Nestlé, Lausanne 26-
Descrição: dc.descriptionDepartment of Pathology and Medical Biology Division of Pathology University of Groningen University Medical Center Groningen (UMCG)-
Descrição: dc.descriptionMedical School (Faculty of Medicine) Sao Paulo State University (UNESP)-
Descrição: dc.descriptionFondo Nacional de Desarrollo Científico y Tecnológico: 1190316-
Descrição: dc.descriptionCAPES: 88882.432902/2019-01-
Idioma: dc.languageen-
Relação: dc.relationMolecular Aspects of Medicine-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDiabesity-
Palavras-chave: dc.subjectExposome-
Palavras-chave: dc.subjectGestational diabesity-
Palavras-chave: dc.subjectGestational diabetes-
Palavras-chave: dc.subjectObesity-
Palavras-chave: dc.subjectVascular-
Título: dc.titleExposome and foetoplacental vascular dysfunction in gestational diabetes mellitus-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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