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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Pontificia Universidad Católica de Chile | - |
Autor(es): dc.contributor | Universidad de Talca | - |
Autor(es): dc.contributor | Universidad de Antofagasta | - |
Autor(es): dc.contributor | Pontificia Universidad Javeriana | - |
Autor(es): dc.contributor | Universidad de Valparaíso | - |
Autor(es): dc.contributor | Hospital Zambrano-Hellion | - |
Autor(es): dc.contributor | Universidad de Sevilla | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (UNESP) | - |
Autor(es): dc.contributor | University of Queensland | - |
Autor(es): dc.contributor | University Medical Center Groningen (UMCG) | - |
Autor(es): dc.contributor | University Medical Center Groningen | - |
Autor(es): dc.contributor | Nestlé Institute for Health Sciences | - |
Autor(es): dc.creator | Valero, Paola | - |
Autor(es): dc.creator | Fuentes, Gonzalo | - |
Autor(es): dc.creator | Cornejo, Marcelo | - |
Autor(es): dc.creator | Vega, Sofía [UNESP] | - |
Autor(es): dc.creator | Grismaldo, Adriana | - |
Autor(es): dc.creator | Pardo, Fabián | - |
Autor(es): dc.creator | García-Rivas, Gerardo | - |
Autor(es): dc.creator | Hillebrands, Jan-Luuk | - |
Autor(es): dc.creator | Faas, Marijke M. | - |
Autor(es): dc.creator | Casanello, Paola | - |
Autor(es): dc.creator | van der Beek, Eline M. | - |
Autor(es): dc.creator | van Goor, Harry | - |
Autor(es): dc.creator | Sobrevia, Luis [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-08-04T22:12:13Z | - |
Data de disponibilização: dc.date.available | 2022-08-04T22:12:13Z | - |
Data de envio: dc.date.issued | 2022-04-28 | - |
Data de envio: dc.date.issued | 2022-04-28 | - |
Data de envio: dc.date.issued | 2020-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.mam.2021.101019 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/222349 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/222349 | - |
Descrição: dc.description | A balanced communication between the mother, placenta and foetus is crucial to reach a successful pregnancy. Several windows of exposure to environmental toxins are present during pregnancy. When the women metabolic status is affected by a disease or environmental toxin, the foetus is impacted and may result in altered development and growth. Gestational diabetes mellitus (GDM) is a disease of pregnancy characterised by abnormal glucose metabolism affecting the mother and foetus. This disease of pregnancy associates with postnatal consequences for the child and the mother. The whole endogenous and exogenous environmental factors is defined as the exposome. Endogenous insults conform to the endo-exposome, and disruptors contained in the immediate environment are the ecto-exposome. Some components of the endo-exposome, such as Selenium, vitamins D and B12, adenosine, and a high-fat diet, and ecto-exposome, such as the heavy metals Arsenic, Mercury, Lead and Copper, and per- and polyfluoroakyl substances, result in adverse pregnancies, including an elevated risk of GDM or gestational diabesity. The impact of the exposome on the human placenta's vascular physiology and function in GDM and gestational diabesity is reviewed. | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | Rijksuniversiteit Groningen | - |
Descrição: dc.description | Universidade Estadual Paulista | - |
Descrição: dc.description | Pontificia Universidad Javeriana | - |
Descrição: dc.description | Fondo Nacional de Desarrollo Científico y Tecnológico | - |
Descrição: dc.description | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
Descrição: dc.description | Cellular and Molecular Physiology Laboratory (CMPL) Department of Obstetrics Division of Obstetrics and Gynaecology School of Medicine Faculty of Medicine Pontificia Universidad Católica de Chile | - |
Descrição: dc.description | Faculty of Health Sciences Universidad de Talca | - |
Descrição: dc.description | Faculty of Health Sciences Universidad de Antofagasta | - |
Descrição: dc.description | Department of Nutrition and Biochemistry Faculty of Sciences Pontificia Universidad Javeriana | - |
Descrição: dc.description | Metabolic Diseases Research Laboratory Interdisciplinary Centre of Territorial Health Research (CIISTe) Biomedical Research Center (CIB) San Felipe Campus School of Medicine Faculty of Medicine Universidad de Valparaíso | - |
Descrição: dc.description | Tecnologico de Monterrey Escuela de Medicina y Ciencias de la Salud Cátedra de Cardiología Hospital Zambrano-Hellion, TecSalud, San Pedro Garza-García | - |
Descrição: dc.description | Department of Obstetrics Division of Obstetrics and Gynaecology and Department of Neonatology Division of Pediatrics School of Medicine Faculty of Medicine Pontificia Universidad Católica de Chile | - |
Descrição: dc.description | Department of Physiology Faculty of Pharmacy Universidad de Sevilla | - |
Descrição: dc.description | Medical School (Faculty of Medicine) Sao Paulo State University (UNESP) | - |
Descrição: dc.description | University of Queensland Centre for Clinical Research (UQCCR) Faculty of Medicine and Biomedical Sciences University of Queensland | - |
Descrição: dc.description | Department of Obstetrics and Gynaecology University of Groningen University Medical Center Groningen (UMCG), Hanzeplein 1, Groningen | - |
Descrição: dc.description | Department of Pediatrics University of Groningen University Medical Center Groningen | - |
Descrição: dc.description | Nestlé Institute for Health Sciences, Nestlé Research, Societé des Produits de Nestlé, Lausanne 26 | - |
Descrição: dc.description | Department of Pathology and Medical Biology Division of Pathology University of Groningen University Medical Center Groningen (UMCG) | - |
Descrição: dc.description | Medical School (Faculty of Medicine) Sao Paulo State University (UNESP) | - |
Descrição: dc.description | Fondo Nacional de Desarrollo Científico y Tecnológico: 1190316 | - |
Descrição: dc.description | CAPES: 88882.432902/2019-01 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Molecular Aspects of Medicine | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Diabesity | - |
Palavras-chave: dc.subject | Exposome | - |
Palavras-chave: dc.subject | Gestational diabesity | - |
Palavras-chave: dc.subject | Gestational diabetes | - |
Palavras-chave: dc.subject | Obesity | - |
Palavras-chave: dc.subject | Vascular | - |
Título: dc.title | Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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