Virucidal activity of the antiseptic mouthwash and dental gel containing anionic phthalocyanine derivative: In vitro study

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Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorTRIALS – Oral Health & Technologies-
Autor(es): dc.creatorSantos, Caique-
Autor(es): dc.creatorOrcina, Bernardo da Fonseca-
Autor(es): dc.creatorReia, Verônica Caroline Brito-
Autor(es): dc.creatorRibeiro, Lucas Gabriel [UNESP]-
Autor(es): dc.creatorGrotto, Rejane M. T. [UNESP]-
Autor(es): dc.creatorPrudenciatti, Aruã [UNESP]-
Autor(es): dc.creatorde Moraes, Leonardo Nazario [UNESP]-
Autor(es): dc.creatorZangrando, Mariana Ragghianti-
Autor(es): dc.creatorVilhena, Fabiano Vieira-
Autor(es): dc.creatorSantos, Paulo Sérgio da Silva-
Data de aceite: dc.date.accessioned2022-08-04T22:10:14Z-
Data de disponibilização: dc.date.available2022-08-04T22:10:14Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.2147/CCIDE.S315419-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/221913-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/221913-
Descrição: dc.descriptionAim: This research suggested an in vitro virucidal action of a dental gel and a mouthwash with phthalocyanine derivative. Purpose: The aim of this study was to report an in vitro study evaluating the virucidal capacity of mouthwash and dental gel containing anionic phthalocyanine derivate (APD). Methods: The research followed the recommendations of the National Health Surveillance Agency (ANVISA) and adapted methodology, described in the standards EN14776: 2015; ASTM E1053-11 and the Robert Koch Institute – RKI, in addition to good laboratory practices (GLP). The determination of the percentage of inactivation of the SARS-CoV-2 virus particles was carried out by imposing the viral solution in contact with the respective tested products, with intervals of 30 seconds, 1 and 5 minutes, with subsequent submission of the aliquots, recovered in cell culture microplates following virus titration using the TCID50 (50% Median Tissue Culture Infectious Dose). Results: The Mouthwash APD presented 90% of viral inactivation percentage, while the dental gel APD demonstrated 99.99% of viral inactivation. Conclusion: In vitro analyses showed that mouthwash and dental gel APD can reduce the viability of SARS-CoV-2 virus particles.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionBauru School of Dentistry University of São Paulo Periodontics-
Descrição: dc.descriptionBauru School of Dentistry University of São Paulo Department of Surgery Stomatology Pathology and Radiology-
Descrição: dc.descriptionBotucatu Medical School São Paulo State University (UNESP)-
Descrição: dc.descriptionTRIALS – Oral Health & Technologies-
Descrição: dc.descriptionBotucatu Medical School São Paulo State University (UNESP)-
Formato: dc.format269-274-
Idioma: dc.languageen-
Relação: dc.relationClinical, Cosmetic and Investigational Dentistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCoronavirus infections-
Palavras-chave: dc.subjectDentifrices-
Palavras-chave: dc.subjectIn vitro techniques-
Palavras-chave: dc.subjectMouthwash-
Título: dc.titleVirucidal activity of the antiseptic mouthwash and dental gel containing anionic phthalocyanine derivative: In vitro study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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