One-Year Update on Salivary Diagnostic of COVID-19

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Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.contributorUniversity of Saskatchewan-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorCaixeta, Douglas Carvalho-
Autor(es): dc.creatorOliveira, Stephanie Wutke-
Autor(es): dc.creatorCardoso-Sousa, Leia-
Autor(es): dc.creatorCunha, Thulio Marquez-
Autor(es): dc.creatorGoulart, Luiz Ricardo-
Autor(es): dc.creatorMartins, Mario Machado-
Autor(es): dc.creatorMarin, Lina Maria-
Autor(es): dc.creatorJardim, Ana Carolina Gomes [UNESP]-
Autor(es): dc.creatorSiqueira, Walter Luiz-
Autor(es): dc.creatorSabino-Silva, Robinson-
Data de aceite: dc.date.accessioned2022-08-04T22:09:52Z-
Data de disponibilização: dc.date.available2022-08-04T22:09:52Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2021-05-21-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3389/fpubh.2021.589564-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/221807-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/221807-
Descrição: dc.descriptionBackground: Coronavirus disease 2019 (COVID-19) is a global health problem, which is challenging healthcare worldwide. In this critical review, we discussed the advantages and limitations in the implementation of salivary diagnostic platforms of COVID-19. The diagnostic test of COVID-19 by invasive nasopharyngeal collection is uncomfortable for patients and requires specialized training of healthcare professionals in order to obtain an appropriate collection of samples. Additionally, these professionals are in close contact with infected patients or suspected cases of COVID-19, leading to an increased contamination risk for frontline healthcare workers. Although there is a colossal demand for novel diagnostic platforms with non-invasive and self-collection samples of COVID-19, the implementation of the salivary platforms has not been implemented for extensive scale testing. Up to date, several cross-section and clinical trial studies published in the last 12 months support the potential of detecting SARS-CoV-2 RNA in saliva as a biomarker for COVID-19, providing a self-collection, non-invasive, safe, and comfortable procedure. Therefore, the salivary diagnosis is suitable to protect healthcare professionals and other frontline workers and may encourage patients to get tested due to its advantages over the current invasive methods. The detection of SARS-CoV-2 in saliva was substantial also in patients with a negative nasopharyngeal swab, indicating the presence of false negative results. Furthermore, we expect that salivary diagnostic devices for COVID-19 will continue to be used with austerity without excluding traditional gold standard specimens to detect SARS-CoV-2.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionInnovation Center in Salivary Diagnostic and Nanotheranostics Department of Physiology Institute of Biomedical Sciences Federal University of Uberlandia-
Descrição: dc.descriptionSchool of Dentistry Federal University of Uberlandia-
Descrição: dc.descriptionSchool of Medicine Federal University of Uberlandia-
Descrição: dc.descriptionInstitute of Genetics and Biochemistry Federal University of Uberlandia-
Descrição: dc.descriptionCollege of Dentistry University of Saskatchewan-
Descrição: dc.descriptionLaboratory of Virology Institute of Biomedical Science Federal University of Uberlandia-
Descrição: dc.descriptionSão Paulo State University Institute of Biosciences Humanities and Exact Sciences-
Descrição: dc.descriptionSão Paulo State University Institute of Biosciences Humanities and Exact Sciences-
Descrição: dc.descriptionCAPES: 1678329P-
Descrição: dc.descriptionCNPq: 465669/2014-0-
Idioma: dc.languageen-
Relação: dc.relationFrontiers in Public Health-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCOVID-19-
Palavras-chave: dc.subjectdiagnostic test-
Palavras-chave: dc.subjectnasopharyngeal swabs-
Palavras-chave: dc.subjectsaliva-
Palavras-chave: dc.subjectsalivary diagnostic-
Palavras-chave: dc.subjectSARS-CoV-2-
Título: dc.titleOne-Year Update on Salivary Diagnostic of COVID-19-
Aparece nas coleções:Repositório Institucional - Unesp

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