Effects of swimming training on the femoral neck strength in growing rats with untreated streptozotocin-induced diabetes

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorFederal University of Vicosa-
Autor(es): dc.contributorFederal University of Viçosa-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorda Silva, Ana Karina-
Autor(es): dc.creatorDel Carlo, Ricardo Junqueira-
Autor(es): dc.creatorda Matta, Sérgio Luis Pinto-
Autor(es): dc.creatorLouzada, Mario Jefferson Quirino-
Autor(es): dc.creatorRodrigues, Aurora Corrêa-
Autor(es): dc.creatorda Silva, Márcia Ferreira-
Autor(es): dc.creatorDrummond, Lucas Rios-
Autor(es): dc.creatorde Castro, Cynthia Aparecida-
Autor(es): dc.creatorSilva, Carlos Henrique Osorio-
Autor(es): dc.creatorNatali, Antônio José-
Data de aceite: dc.date.accessioned2022-08-04T22:04:52Z-
Data de disponibilização: dc.date.available2022-08-04T22:04:52Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2014-12-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/220426-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/220426-
Descrição: dc.descriptionBackground: While type 1 diabetes mellitus (T1DM) increases bone fragility physical exercise improves bone quality and strength. Research question: To test whether swimming training attenuates the deterioration of femoral neck structural and mechanical properties in growing rats with untreated streptozotocin (STZ)-induced T1DM. Type of study: Randomised controlled study. Methods: Male Wistar rats (4-weeks-old; initial body weight: 80-90 g) were divided into 4 groups of 10 animals: diabetes sedentary (DS; 60 mg/kg of STZ, single i.p.); diabetes exercised (DE; 60 mg/kg of STZ, single i.p.); control sedentary (CS, same single dose of vehicle); and control exercised (CE, same single dose of vehicle). Six weeks later animals from DE and CE groups underwent a low- intensity swimming training (5 sessions/wk, 90 min/session, load: 4% of body weight) for 8 weeks. The femoral neck mechanical properties were measured. Bone mineral density (BMD) and mineral content (BMC), as well as the femoral neck bone volume (BV/TV) and collagen content were assessed. Results: Rats with T1DM exhibited reduced body weight, femoral weight and length, BMC and BMD, femoral neck collagen content, BV/TV, trabecular thickness, maximum load, stiffness and tenacity, and increased trabecular spacing compared to controls. Swimming training increased femoral BMC and BMD, femoral neck collagen content, BV/TV, trabecular thickness, stiffness and yield point energy, and reduced trabecular spacing in control animals, but not in T1DM animals. Conclusion: Low-intensity swimming training seems to be ineffective in attenuating the deterioration of the femoral neck structural and mechanical properties in growing rats with untreated STZ-induced T1DM.-
Descrição: dc.descriptionDepartment of Physical Education Federal University of Vicosa-
Descrição: dc.descriptionDepartment of Veterinary Federal University of Vicosa-
Descrição: dc.descriptionDepartment of General Biology Federal University of Viçosa-
Descrição: dc.descriptionSchool of Veterinary Medicine State University of São Paulo-
Descrição: dc.descriptionDepartment of Statistics Federal University of Vicosa-
Formato: dc.format445-457-
Idioma: dc.languageen-
Relação: dc.relationInternational SportMed Journal-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBone resistance-
Palavras-chave: dc.subjectExercise-
Palavras-chave: dc.subjectHip fracture-
Palavras-chave: dc.subjectOsteopenia-
Palavras-chave: dc.subjectPhysical activity-
Título: dc.titleEffects of swimming training on the femoral neck strength in growing rats with untreated streptozotocin-induced diabetes-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.