Optimization and application of imprinted poly(AA-EGDMA) for solid phase extraction of ciprofloxacin in artificial urine

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFederal Institute of Paraná-
Autor(es): dc.contributorUniversidade Estadual de Londrina (UEL)-
Autor(es): dc.creatorMarestoni, Luis D. [UNESP]-
Autor(es): dc.creatorWong, Ademar [UNESP]-
Autor(es): dc.creatorFeliciano, Gustavo T. [UNESP]-
Autor(es): dc.creatorMarchi, Mary R. R. [UNESP]-
Autor(es): dc.creatorTarley, Cesar R. T.-
Autor(es): dc.creatorDel Pilar Taboada Sotomayor, Maria [UNESP]-
Data de aceite: dc.date.accessioned2022-08-04T22:04:42Z-
Data de disponibilização: dc.date.available2022-08-04T22:04:42Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2015-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.2174/1574885510999150505160637-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/220377-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/220377-
Descrição: dc.descriptionCiprofloxacin is one of the most widely used antibiotics and knowledge of concentration in the urine is of great significance for pharmacokinetic and environmental studies. In this work, the Poly (Acrylic Acid – Ethylene Glycol Dimethacrylate) Molecularly Imprinted Polymer was optimized as a adsorbent in solid phase extraction (MISPE) for Ciprofloxacin. It is desirable because they are adsorbent materials highly selective to their template molecule. The MIP resulted in maximum sorption capacities of 282 μmol g-1 in batch studies and in μmol g-1 in the breakthrough curve studies. MISPE was applied in synthetic urine to test its viability. The limit of detection was 70 ng mL-1. The enrichment factor of the method was 5.32, and recovery in urine ranged from 94.2% to 120.8%. These results showed the applicability of this optimized MISPE.-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University, Prof. Francisco Degni Street, 55-
Descrição: dc.descriptionFederal Institute of Paraná, Highway PR160, km19.5-
Descrição: dc.descriptionDepartment of Chemistry State University of Londrina, Highway Celso Garcia Cid, km380-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University, Prof. Francisco Degni Street, 55-
Formato: dc.format270-276-
Idioma: dc.languageen-
Relação: dc.relationCurrent Drug Therapy-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCiprofloxacin-
Palavras-chave: dc.subjectMolecularly imprinted polymers-
Palavras-chave: dc.subjectOptimization-
Palavras-chave: dc.subjectSolid phase extraction-
Título: dc.titleOptimization and application of imprinted poly(AA-EGDMA) for solid phase extraction of ciprofloxacin in artificial urine-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.