Evaluating the acute contributions of dopaminergic replacement to gait with obstacles in parkinson's disease

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorWilfrid Laurier University-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorUniversity of Waterloo-
Autor(es): dc.creatorPieruccini-Faria, F.-
Autor(es): dc.creatorVitório, R.-
Autor(es): dc.creatorAlmeida, Q. J.-
Autor(es): dc.creatorSilveira, C. R.A.-
Autor(es): dc.creatorCaetano, M. J.D.-
Autor(es): dc.creatorStella, F.-
Autor(es): dc.creatorGobbi, S.-
Autor(es): dc.creatorGobbi, L. T.B.-
Data de aceite: dc.date.accessioned2022-08-04T22:03:30Z-
Data de disponibilização: dc.date.available2022-08-04T22:03:30Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2013-11-25-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/00222895.2013.810139-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/219976-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/219976-
Descrição: dc.descriptionThe influence of dopaminergic replacement (DR) on gait in people with Parkinson's disease (PD) is well documented. However, little is known about the acute effects of dopamine on more complex locomotor tasks that require visual guidance to avoid obstacles during gait. The authors investigated the influence of DR on locomotor behavior in a task where movement planning and control might be challenged by the height of the obstacle. The PD group included patients diagnosed with idiopathic PD (n = 12), as well as healthy controls (n = 12). Patients walked and stepped over obstacles of different heights before (OFF) and after (ON) levodopa intake. Spatial adjustments were not modulated by DR, but the step time to perform these anticipatory gait adjustments was longer only in PD-OFF (compared with healthy controls) when approaching the highest obstacle, but not PD-ON. During the crossing phase, trail limb toe clearance of PD patients was shorter than healthy controls only during the OFF state. ON-OFF comparisons were significantly different only for the time to reach the lead foot clearance over the highest obstacle. In summary, DR partially improved movement slowness but did not directly affect movement amplitude of lower limb regulation in this gait task. Copyright © 2013 Taylor & Francis Group.-
Descrição: dc.descriptionPhysical Education Department Posture and Gait Studies Lab University of Sao Paulo State-
Descrição: dc.descriptionSun Life Financial Movement Disorders Research and Rehabilitation Centre Wilfrid Laurier University, 66 Hickory Street West, Waterloo, ON N2L 3C5-
Descrição: dc.descriptionFaculty of Medical Sciences Campinas State University, Campinas-
Descrição: dc.descriptionKinesiology Department University of Waterloo, ON-
Formato: dc.format369-380-
Idioma: dc.languageen-
Relação: dc.relationJournal of Motor Behavior-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAdaptive gait-
Palavras-chave: dc.subjectDopaminergic replacement-
Palavras-chave: dc.subjectLocomotion-
Palavras-chave: dc.subjectObstacle crossing-
Palavras-chave: dc.subjectObstacle heights-
Palavras-chave: dc.subjectParkinson's disease-
Título: dc.titleEvaluating the acute contributions of dopaminergic replacement to gait with obstacles in parkinson's disease-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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