Gender, body mass index and rheumatoid arthritis disease activity: Results from the QUEST-RA study

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Autor(es): dc.contributorUniversity of California Los Angeles-
Autor(es): dc.contributorUniversity of California Berkeley-
Autor(es): dc.contributorNorth Karelia Central Hospital-
Autor(es): dc.contributorPontifícia Universidade Católica do Rio Grande do Sul (PUCRS)-
Autor(es): dc.contributorUniversidade Federal do Ceará-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorHospital Universitário de Brasília-
Autor(es): dc.contributorUniversity of Ioannina Ioannina-
Autor(es): dc.contributorWaterford Regional Hospital-
Autor(es): dc.contributorConnolly Hospital-
Autor(es): dc.contributorUniversity of Genova-
Autor(es): dc.contributorRheumatology Department-
Autor(es): dc.contributorVilnius University-
Autor(es): dc.contributorUniversity Medical Centre Utrecht-
Autor(es): dc.contributorJyväskylä Central Hospital-
Autor(es): dc.contributorMedcare Oy-
Autor(es): dc.contributorHospital Oakland Research Institute-
Autor(es): dc.contributorHospital San Juan Bautista-
Autor(es): dc.contributorHospital of Cordoba-
Autor(es): dc.contributorUniversidade do Estado do Rio de Janeiro (UERJ)-
Autor(es): dc.contributorRiverside Professional Centre-
Autor(es): dc.contributorCopenhagen University Hospital at Hvidovre-
Autor(es): dc.contributorKing Christian the Xth Hospital-
Autor(es): dc.contributorCopenhagen University Hospital at Herlev-
Autor(es): dc.contributorAl-Azhar University-
Autor(es): dc.contributorAssiut University Hospital-
Autor(es): dc.contributorAbo Sohage University Hospital-
Autor(es): dc.contributorTartu University Hospital-
Autor(es): dc.contributorEast-Tallinn Central Hospital-
Autor(es): dc.contributorCentre for Clinical and Basic Research-
Autor(es): dc.contributorSatakunta Central Hospital-
Autor(es): dc.contributorHôpital Cochin-
Autor(es): dc.contributorINSERM U887-
Autor(es): dc.contributorHôpital Lapeyronie-
Autor(es): dc.contributorHôpital Hautepierre-
Autor(es): dc.contributorNational University of Athens-
Autor(es): dc.contributorEuroclinic Hospital-
Autor(es): dc.contributorEvangelisches Fachkrankenhaus-
Autor(es): dc.contributorSchlosspark-Klinik-
Autor(es): dc.contributorUniversity Medicine Berlin-
Autor(es): dc.contributorSemmelweis University of Medical Sciences-
Autor(es): dc.contributorPolyclinic of the Hospitaller Brothers of St. John of God in Budapest-
Autor(es): dc.contributorSt. Vincent University Hospital-
Autor(es): dc.contributorOur Lady's Hospice-
Autor(es): dc.contributorVedanta Institiute of Medical Sciences-
Autor(es): dc.contributorJaipur Hospital-
Autor(es): dc.contributorSanta Chiara Hospital-
Autor(es): dc.contributorCatholic University of Sacred Heart-
Autor(es): dc.contributorUniversity of Ancona-
Autor(es): dc.contributorTokyo Women's Medical University-
Autor(es): dc.contributorKyoto First Red Cross Hospital-
Autor(es): dc.contributorShono Rheumatism Clinic-
Autor(es): dc.contributorKenyatta Hospital-
Autor(es): dc.contributorPauls Stradina Clinical University Hospital-
Autor(es): dc.contributorKaunas University Hospital-
Autor(es): dc.contributorEl Ayachi Hospital Mohamed Vth Souissi University-
Autor(es): dc.contributorSint Franciscus Gasthuis Hospital-
Autor(es): dc.contributorMedisch Spectrum Twente-
Autor(es): dc.contributorSørlandet Hospital-
Autor(es): dc.contributorMedical University in Bialystok-
Autor(es): dc.contributorMedical University of Lublin-
Autor(es): dc.contributorPoznan Rheumatology Centre in Srem-
Autor(es): dc.contributorMilitary Institute of Medicine-
Autor(es): dc.contributorSilesian Hospital for Rheumatology and Rehabilitation in Ustron Slaski-
Autor(es): dc.contributorSzpital Wojewodzki im. Jana Biziela-
Autor(es): dc.contributorWojewodzki Zespol Reumatologiczny im. dr Jadwigi Titz-Kosko-
Autor(es): dc.contributorSpitalul Clinic Sf Maria-
Autor(es): dc.contributorInstitute of Rheumatology of Russian Academy of Medical Sciences-
Autor(es): dc.contributorMoscow Medical Academy-
Autor(es): dc.contributorRussian Medical Academy of Postgraduate Education-
Autor(es): dc.contributorRheumatology Institut-
Autor(es): dc.contributorHospital de Gran Canaria Dr. Negrin-
Autor(es): dc.contributorHospital Sierrallana Ganzo-
Autor(es): dc.contributorHospital General de Castellón-
Autor(es): dc.contributorUppsala University Hospital-
Autor(es): dc.contributorCentrallasarettet-
Autor(es): dc.contributorHudiksvall Medical Clinic-
Autor(es): dc.contributorGazi University Medical Faculty-
Autor(es): dc.contributorMeram Medical Faculty-
Autor(es): dc.contributorCerrahpasa Medic Faculty-
Autor(es): dc.contributorDubai Bone and Joint Centre-
Autor(es): dc.contributorAmerican Hospital Dubai-
Autor(es): dc.contributorCharing Cross Hospital-
Autor(es): dc.contributorRoyal Cornwall Hospital-
Autor(es): dc.contributorKings College Hospital-
Autor(es): dc.contributorVanderbilt University-
Autor(es): dc.contributorNYU Hospital for Joint Diseases-
Autor(es): dc.contributorTaylor Hospital-
Autor(es): dc.contributorCentra Care Clinic-
Autor(es): dc.contributorUniversity of Arkansas for Medical Sciences-
Autor(es): dc.contributorNew York University Hospital for Joint Diseases-
Autor(es): dc.creatorJawaheer, Damini-
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Autor(es): dc.creatorDrosos, Alexandros A.-
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Autor(es): dc.creatorAlba, Paula-
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Autor(es): dc.creatorLiveborn, Margareth-
Autor(es): dc.creatorHolmqvist, Ann-Carin-
Autor(es): dc.creatorGogus, Feride-
Autor(es): dc.creatorTunc, Recep-
Autor(es): dc.creatorCelic, Selda-
Autor(es): dc.creatorBadsha, Humeira-
Autor(es): dc.creatorMofti, Ayman-
Autor(es): dc.creatorTaylor, Peter-
Autor(es): dc.creatorMcClinton, Catherine-
Autor(es): dc.creatorWoolf, Anthony-
Autor(es): dc.creatorChorghade, Ginny-
Autor(es): dc.creatorChoy, Ernest-
Autor(es): dc.creatorKelly, Stephen-
Autor(es): dc.creatorPincus, Theodore-
Autor(es): dc.creatorYazici, Yusuf-
Autor(es): dc.creatorBergman, Martin-
Autor(es): dc.creatorCraig-Muller, Jurgen-
Autor(es): dc.creatorKautiainen, Hannu-
Autor(es): dc.creatorSwearingen, Christopher-
Data de aceite: dc.date.accessioned2022-08-04T22:02:19Z-
Data de disponibilização: dc.date.available2022-08-04T22:02:19Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2010-12-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/219633-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/219633-
Descrição: dc.descriptionObjective: To investigate whether body mass index (BMI), as a proxy for body fat, influences rheumatoid arthritis (RA) disease activity in a gender-specific manner. Methods: Consecutive patients with RA were enrolled from 25 countries into the QUEST-RA program between 2005 and 2008. Clinical and demographic data were collected by treating rheumatologists and by patient self-report. Distributions of Disease Activity Scores (DAS28), BMI, age, and disease duration were assessed for each country and for the entire dataset; mean values between genders were compared using Student's t-tests. An association between BMI and DAS28 was investigated using linear regression, adjusting for age, disease duration and country. Results: A total of 5,161 RA patients (4,082 women and 1,079 men) were included in the analyses. Overall, women were younger, had longer disease duration, and higher DAS28 scores than men, but BMI was similar between genders. The mean DAS28 scores increased with increasing BMI from normal to overweight and obese, among women, whereas the opposite trend was observed among men. Regression results showed BMI (continuous or categorical) to be associated with DAS28. Compared to the normal BMI range, being obese was associated with a larger difference in mean DAS28 (0.23, 95% CI: 0.11, 0.34) than being overweight (0.12, 95% CI: 0.03, 0.21); being underweight was not associated with disease activity. These associations were more pronounced among women, and were not explained by any single component of the DAS28. Conclusion: BMI appears to be associated with RA disease activity in women, but not in men. © Copyright Clinical and Experimental Rheumatology 2010.-
Descrição: dc.descriptionUniversity of California Los Angeles, Los Angeles, CA-
Descrição: dc.descriptionUniversity of California Berkeley, Berkeley, CA-
Descrição: dc.descriptionNorth Karelia Central Hospital, Joensuu-
Descrição: dc.descriptionPontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre-
Descrição: dc.descriptionUniversidade Federal do Ceará, Fortaleza-
Descrição: dc.descriptionUniversidade Estadual de São Paulo, São Paulo-
Descrição: dc.descriptionHospital Universitário de Brasília, Brasilia-
Descrição: dc.descriptionUniversity of Ioannina Ioannina-
Descrição: dc.descriptionWaterford Regional Hospital, Waterford-
Descrição: dc.descriptionConnolly Hospital, Dublin-
Descrição: dc.descriptionUniversity of Genova, Genova-
Descrição: dc.descriptionRheumatology Department, Pristine-
Descrição: dc.descriptionInstitute of Experimental and Clinical Medicine Vilnius University, Vilnius-
Descrição: dc.descriptionUniversity Medical Centre Utrecht, Utrecht-
Descrição: dc.descriptionJyväskylä Central Hospital, Jyväskylä-
Descrição: dc.descriptionMedcare Oy, Äänekoski-
Descrição: dc.descriptionHospital Oakland Research Institute, Oakland, CA-
Descrição: dc.descriptionHospital San Juan Bautista, Catamarca-
Descrição: dc.descriptionHospital of Cordoba, Cordoba-
Descrição: dc.descriptionUniversidade do Estado do Rio de Janeiro, Rio de Janeiro-
Descrição: dc.descriptionRiverside Professional Centre, Sydney, NS-
Descrição: dc.descriptionCopenhagen University Hospital at Hvidovre, Hvidovre-
Descrição: dc.descriptionKing Christian the Xth Hospital, Gråsten-
Descrição: dc.descriptionCopenhagen University Hospital at Herlev, Herlev-
Descrição: dc.descriptionAl-Azhar University, Cairo-
Descrição: dc.descriptionAssiut University Hospital, Assiut-
Descrição: dc.descriptionAbo Sohage University Hospital, Sohage-
Descrição: dc.descriptionTartu University Hospital, Tartu-
Descrição: dc.descriptionEast-Tallinn Central Hospital, Tallinn-
Descrição: dc.descriptionCentre for Clinical and Basic Research, Tallinn-
Descrição: dc.descriptionSatakunta Central Hospital, Rauma-
Descrição: dc.descriptionUniversity René Descartes Hôpital Cochin, Paris-
Descrição: dc.descriptionDijon University Hospital University of Burgundy INSERM U887, Dijon-
Descrição: dc.descriptionHôpital Lapeyronie, Montpellier-
Descrição: dc.descriptionHôpital Hautepierre, Strasbourg-
Descrição: dc.descriptionSchool of Medicine National University of Athens, Athens-
Descrição: dc.descriptionEuroclinic Hospital, Athens-
Descrição: dc.descriptionEvangelisches Fachkrankenhaus, Ratingen-
Descrição: dc.descriptionSchlosspark-Klinik, Berlin-
Descrição: dc.descriptionUniversity Medicine Berlin, Berlin-
Descrição: dc.descriptionSemmelweis University of Medical Sciences, Budapest-
Descrição: dc.descriptionIlona Újfalussy Polyclinic of the Hospitaller Brothers of St. John of God in Budapest, Budapest-
Descrição: dc.descriptionSt. Vincent University Hospital, Dublin-
Descrição: dc.descriptionOur Lady's Hospice, Dublin-
Descrição: dc.descriptionDepartment of Immunology, Lucknow-
Descrição: dc.descriptionVedanta Institiute of Medical Sciences, Ahmedabad-
Descrição: dc.descriptionDepartment of Immunology Jaipur Hospital-
Descrição: dc.descriptionSanta Chiara Hospital, Pisa-
Descrição: dc.descriptionCatholic University of Sacred Heart, Rome-
Descrição: dc.descriptionUniversity of Ancona, Ancona-
Descrição: dc.descriptionInstitute of Rheumatology Tokyo Women's Medical University, Tokyo-
Descrição: dc.descriptionDepartment of Rheumatology Kyoto First Red Cross Hospital, Kyoto-
Descrição: dc.descriptionShono Rheumatism Clinic, Fukuoka-
Descrição: dc.descriptionKenyatta Hospital, Nairobi-
Descrição: dc.descriptionPauls Stradina Clinical University Hospital, Riga-
Descrição: dc.descriptionKaunas University Hospital, Kaunas-
Descrição: dc.descriptionEl Ayachi Hospital Mohamed Vth Souissi University, Rabat-
Descrição: dc.descriptionSint Franciscus Gasthuis Hospital, Rotterdam-
Descrição: dc.descriptionMedisch Spectrum Twente, Enschede-
Descrição: dc.descriptionSørlandet Hospital, Kristiansand-
Descrição: dc.descriptionMedical University in Bialystok, Bialystok-
Descrição: dc.descriptionMedical University of Lublin, Lublin-
Descrição: dc.descriptionPoznan Rheumatology Centre in Srem, Srem-
Descrição: dc.descriptionMilitary Institute of Medicine, Warsaw-
Descrição: dc.descriptionSilesian Hospital for Rheumatology and Rehabilitation in Ustron Slaski, Ustroñ Slaski-
Descrição: dc.descriptionSzpital Wojewodzki im. Jana Biziela, Bydgoszcz-
Descrição: dc.descriptionWojewodzki Zespol Reumatologiczny im. dr Jadwigi Titz-Kosko, Sopot-
Descrição: dc.descriptionSpitalul Clinic Sf Maria, Bucharest-
Descrição: dc.descriptionInstitute of Rheumatology of Russian Academy of Medical Sciences, Moscow-
Descrição: dc.descriptionMoscow Medical Academy, Moscow-
Descrição: dc.descriptionRussian Medical Academy of Postgraduate Education, Moscow-
Descrição: dc.descriptionRheumatology Institut, Niska Banja-
Descrição: dc.descriptionHospital de Gran Canaria Dr. Negrin, Las Palmas-
Descrição: dc.descriptionHospital Sierrallana Ganzo, Torrelavega-
Descrição: dc.descriptionHospital General de Castellón, Castellón-
Descrição: dc.descriptionUppsala University Hospital, Uppsala-
Descrição: dc.descriptionCentrallasarettet, Västerås-
Descrição: dc.descriptionHudiksvall Medical Clinic, Hudiksvall-
Descrição: dc.descriptionGazi University Medical Faculty, Ankara-
Descrição: dc.descriptionMeram Medical Faculty, Konya-
Descrição: dc.descriptionCerrahpasa Medic Faculty, Istanbul-
Descrição: dc.descriptionDubai Bone and Joint Centre, Dubai-
Descrição: dc.descriptionAmerican Hospital Dubai, Dubai-
Descrição: dc.descriptionCharing Cross Hospital, London-
Descrição: dc.descriptionRoyal Cornwall Hospital, Truro-
Descrição: dc.descriptionKings College Hospital, London-
Descrição: dc.descriptionVanderbilt University, Nashville, TN-
Descrição: dc.descriptionNYU Hospital for Joint Diseases, New York, NY-
Descrição: dc.descriptionTaylor Hospital, Ridley Park, PA-
Descrição: dc.descriptionCentra Care Clinic, St. Cloud, MN-
Descrição: dc.descriptionUniversity of Arkansas for Medical Sciences, Little Rock, AR-
Descrição: dc.descriptionNew York University Hospital for Joint Diseases, New York, NY-
Descrição: dc.descriptionUniversidade Estadual de São Paulo, São Paulo-
Formato: dc.format454-461-
Idioma: dc.languageen-
Relação: dc.relationClinical and Experimental Rheumatology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBmi-
Palavras-chave: dc.subjectDisease activity-
Palavras-chave: dc.subjectGender-
Palavras-chave: dc.subjectRheumatoid arthritis-
Título: dc.titleGender, body mass index and rheumatoid arthritis disease activity: Results from the QUEST-RA study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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