Racial differences in prostate cancer prevalence

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorAntonopoulos, Ioannis M.-
Autor(es): dc.creatorPompeo, Antonio C.L.-
Autor(es): dc.creatorDe Góes, Plínio M.-
Autor(es): dc.creatorChade, Jamil-
Autor(es): dc.creatorSarkis, Alvaro S.-
Autor(es): dc.creatorArap, Sami-
Data de aceite: dc.date.accessioned2022-08-04T22:01:11Z-
Data de disponibilização: dc.date.available2022-08-04T22:01:11Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2002-01-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/219264-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/219264-
Descrição: dc.descriptionObjective: To evaluate racial differences in prostate cancer prevalence in Brazil. Materials and Methods: We evaluated 1,773 men submitted to digital rectal examination (DRE), serum total prostate-specific antigen (PSA) assay, and the AUA-IPSS questionnaire from 1992 to 1997. They were classified according to the race in whites (1180 men), blacks (201 men) and yellows (45 men). Racial classification was not possible in 347 men. When PSA and/or DRE were abnormal, transrectal ultrasound guided prostate biopsy was indicated. Clinical stage and Gleason score were recorded and racial prevalence were compared. Results: 346 biopsies were performed and 51 cancers were diagnosed (positive biopsy rate of 14.7%). The distribution of PSA among these cancer cases was normal PSA in 4 (7.8%), between 4 ng/ml and 10 ng/ml in 16 (31.4%), and PSA > 10 ng/ml in 31 (60.8%). The cancer prevalence in white men was 2.4% and in black men 5.5% (p < 0.05). White men median age was 62.3 ± 0.4 and black men median age was 62.4 ± 0.7 (p > 0.05). Median PSA was 3 ng/ml for white men and 3.3 ng/ml for black men (p > 0.05). Black men had higher prevalence of abnormal DRE (18.9% versus 11.7%, p < 0.05). Median education class for white men was 3 and for black men 2 (p < 0.05). Prevalence of clinically localized cancer was 61.3%. Conclusions: The prevalence of prostate cancer is higher in blacks than in whites (5.5% versus 2.4%). The median PSA was similar for both racial groups. DRE abnormalities in black men were more prevalent than in white men (18.9% versus 11.7%).-
Descrição: dc.descriptionDivision of Urology School of Medicine State Univ. of São Paulo USP, Rua Jaraguá 192, São Paulo, SP 01129-000-
Formato: dc.format214-219-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Journal of Urology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDiagnosis-
Palavras-chave: dc.subjectEpidemiology-
Palavras-chave: dc.subjectProstate-
Palavras-chave: dc.subjectProstatic neoplasm-
Título: dc.titleRacial differences in prostate cancer prevalence-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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