A Cellular and Endocrine Characterization of the Original and Induced Corpus Luteum after Administration of a Gonadotropin-Releasing Hormone Agonist or Human Chorionic Gonadotropin on Day Five of the Estrous Cycle

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversity of Florida-
Autor(es): dc.contributorUniv. Estadual de São Paulo-
Autor(es): dc.contributorUniversity of South Alabama-
Autor(es): dc.creatorSchmitt, É J.P.-
Autor(es): dc.creatorBarros, C. M.-
Autor(es): dc.creatorFields, P. A.-
Autor(es): dc.creatorFields, M. J.-
Autor(es): dc.creatorDiaz, T.-
Autor(es): dc.creatorKluge, J. M.-
Autor(es): dc.creatorThatcher, W. W.-
Data de aceite: dc.date.accessioned2022-08-04T22:01:01Z-
Data de disponibilização: dc.date.available2022-08-04T22:01:01Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued1996-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.2527/1996.7481915x-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/219194-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/219194-
Descrição: dc.descriptionTo determine whether injection of hCG or GnRH-agonist on d 5 after estrus (d 0) has a differential functional effect on an induced and the original corpus luteum (CL), two experiments were conducted. In Exp. 1, nonlactating Holstein cows were injected on d 5 with saline (n = 4; T1), a GnRH-agonist (Buserelin®, 8 μg i.m.; n = 4; T2), or hCG (1,000 IU, i.v., and 2,000 IU, i.m.; n = 4; T3). Induced CL were removed on d 13 and weights were different (GnRH-agonist < hCG). In vitro production of progesterone by CL tissue (μg/g; μg/CL) was affected by treatment (GnRH-agonist < hCG) and dose of LH (ng/mL) in culture media. Experiment 2 was a replicate of Exp. 1, except that the original CL was removed on d 17 for in vitro culture. Day-17 CL weights and in vitro production of progesterone by original CL were not affected by treatment. The daily rate of increase of plasma progesterone from d 6 to d 13 differed: saline < GnRH-agonist < hCG (P < .01). From d 14 to 17, the rate of plasma progesterone decrease was not different between treatments. Electron micrographic study of the original and induced CL indicates that LH-like exposure delays involution of steroidogenic luteal cells. In summary, the higher levels of progesterone from d 6 to d 13 of the estrous cycle following an injection of hCG vs GnRH-agonist on d 5 is due to a greater response of hCG-induced CL.-
Descrição: dc.descriptionDept. of Dairy and Poultry Sciences University of Florida, Gainesville, FL 32611-
Descrição: dc.descriptionDepartment of Animal Science University of Florida, Gainesville, FL 32611-
Descrição: dc.descriptionDepartment of Pharmacology Univ. Estadual de São Paulo, São Paulo 18600-
Descrição: dc.descriptionDept. of Struct. and Cell. Biology University of South Alabama, Mobile, AL 36688-
Formato: dc.format1915-1929-
Idioma: dc.languageen-
Relação: dc.relationJournal of Animal Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCorpus Luteum-
Palavras-chave: dc.subjectGonadotropins-
Palavras-chave: dc.subjecthCG-
Palavras-chave: dc.subjectLuteal Cells-
Palavras-chave: dc.subjectProgesterone-
Título: dc.titleA Cellular and Endocrine Characterization of the Original and Induced Corpus Luteum after Administration of a Gonadotropin-Releasing Hormone Agonist or Human Chorionic Gonadotropin on Day Five of the Estrous Cycle-
Tipo de arquivo: dc.typelivro digital-
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