High dietary carbohydrate and pancreatic lesion.

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorNovelli, E. L. [UNESP]-
Autor(es): dc.creatorRodrigues, N. L. [UNESP]-
Autor(es): dc.creatorFrança, E. L. [UNESP]-
Autor(es): dc.creatorGebra, L. M. [UNESP]-
Autor(es): dc.creatorRibas, B. O. [UNESP]-
Data de aceite: dc.date.accessioned2022-08-04T22:00:55Z-
Data de disponibilização: dc.date.available2022-08-04T22:00:55Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued1993-01-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/219160-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/219160-
Descrição: dc.descriptionThe ability of high dietary carbohydrate to induce acute pancreatitis was investigated in groups of 16, 21-day and 15-month old rats fed different carbohydrate diets for 30 days. Significantly increased levels of serum amylase (2-fold), phospholipids (50%), phosphorus (2-fold), and lipoperoxides (8-fold) were observed in 15-month old rats fed a high-carbohydrate diet, compared to rats fed a diet with normal carbohydrate levels, indicating peroxidation of membrane lipids which caused final cell death and pancreatic lesion. Serum Cu-Zn superoxide dismutase activity was not altered. Daily administration of bovine Cu-Zn superoxide dismutase conjugated with polyethylene glycol prevented the serum level alterations and pancreatic lesions, indicating that the superoxide radical has a role in dietary carbohydrate-induced acute pancreatitis. No biochemical changes were observed in rats in which treatment was initiated on the 21st day of life indicating that this is an age-related lesion.-
Descrição: dc.descriptionDepartamento de Química Universidade Estadual Paulista SP-
Descrição: dc.descriptionDepartamento de Química Universidade Estadual Paulista SP-
Formato: dc.format31-36-
Idioma: dc.languageen-
Relação: dc.relationBrazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]-
???dc.source???: dc.sourceScopus-
Título: dc.titleHigh dietary carbohydrate and pancreatic lesion.-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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