Zebrafish as an alternative animal model in human and animal vaccination research

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorFed Inspect Serv-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorHarper Adams Univ-
Autor(es): dc.creatorBailone, Ricardo Lacava [UNESP]-
Autor(es): dc.creatorFukushima, Hirla Costa Silva-
Autor(es): dc.creatorVentura Fernandes, Bianca Helena-
Autor(es): dc.creatorDe Aguiar, Luis Kluwe-
Autor(es): dc.creatorCorrea, Tatiana-
Autor(es): dc.creatorJanke, Helena-
Autor(es): dc.creatorGrejo Setti, Princia-
Autor(es): dc.creatorRoca, Roberto De Oliveira [UNESP]-
Autor(es): dc.creatorBorra, Ricardo Carneiro-
Data de aceite: dc.date.accessioned2022-08-04T21:59:42Z-
Data de disponibilização: dc.date.available2022-08-04T21:59:42Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2020-05-07-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1186/s42826-020-00042-4-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/218915-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/218915-
Descrição: dc.descriptionMuch of medical research relies on animal models to deepen knowledge of the causes of animal and human diseases, as well as to enable the development of innovative therapies. Despite rodents being the most widely used research model worldwide, in recent decades, the use of the zebrafish (Danio rerio) model has exponentially been adopted among the scientific community. This is because such a small tropical freshwater teleost fish has crucial genetic, anatomical and physiological homology with mammals. Therefore, zebrafish constitutes an excellent experimental model for behavioral, genetic and toxicological studies which unravels the mechanism of various human diseases. Furthermore, it serves well to test new therapeutic agents, such as the safety of new vaccines. The aim of this review was to provide a systematic literature review on the most recent studies carried out on the topic. It presents numerous advantages of this type of animal model in tests of efficacy and safety of both animal and human vaccines, thus highlighting gains in time and cost reduction of research and analyzes.-
Descrição: dc.descriptionFed Inspect Serv, Minist Agr Livestock & Supply, Sao Carlos, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Botucatu, SP, Brazil-
Descrição: dc.descriptionUniv Fed Sao Carlos, Fed Univ, Hlth & Biol Sci Ctr, Sao Carlos, SP, Brazil-
Descrição: dc.descriptionUniv Sao Paulo, Tech Directorate Teaching & Res Support, Sao Paulo, SP, Brazil-
Descrição: dc.descriptionHarper Adams Univ, Dept Food Technol & Innovat, Newport, Shrops, England-
Descrição: dc.descriptionUniv Fed Sao Carlos, Dept Genet & Evolut, Sao Carlos, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Botucatu, SP, Brazil-
Formato: dc.format10-
Idioma: dc.languageen-
Publicador: dc.publisherSpringer-
Relação: dc.relationLaboratory Animal Research-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subject3Rs-
Palavras-chave: dc.subjectAnimal health-
Palavras-chave: dc.subjectHuman health-
Palavras-chave: dc.subjectImmunity-
Palavras-chave: dc.subjectToxicology-
Palavras-chave: dc.subjectVaccine safety-
Título: dc.titleZebrafish as an alternative animal model in human and animal vaccination research-
Aparece nas coleções:Repositório Institucional - Unesp

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