ANTI-ALZHEIMER ACTIVITY OF SUBSTANCES FROM NATURAL PRODUCTS AND OF SYNTHETIC ORIGIN: SOME IMPORTANT EXAMPLES OF THE LAST 20 YEARS.

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniv Fed Jatai-
Autor(es): dc.creatorSilva Vellosa, Ana Beatriz [UNESP]-
Autor(es): dc.creatorLima Filho, Valdinei Bueno-
Autor(es): dc.creatorSoares, Breno Almeida-
Autor(es): dc.creatorNascimento-Junior, Nailton [UNESP]-
Data de aceite: dc.date.accessioned2022-08-04T21:59:17Z-
Data de disponibilização: dc.date.available2022-08-04T21:59:17Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-02-03-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.21577/0100-4042.20170860-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/218803-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/218803-
Descrição: dc.descriptionAlzheimer's disease has about 9.9 million new cases annually, according to World Health Organization. Due to the increasing incidence of people affected by AD and the absence of an efficient treatment or cure so far, many researchers worldwide are involved in the search for novel promising drugs candidates, through several targets, exploring distinct structural patterns. In this context, we describe herein, focusing the last 20 years, strategic examples of substances with targets related to Alzheimer's disease derived from natural products, such as alkaloids, chalcones, coumarins and flavonoids, in addition to carbamates and heterocyclic compounds. Furthermore, some cases are discussed where computational chemistry is used to better understand protein-ligand interactions.-
Descrição: dc.descriptionUniv Estadual Paulista, Inst Quim, Dept Bioquim & Quim Organ, Lab Quim Med Sintese Organ & Modelagem Mol LaQMed, BR-14800060 Araraquara, SP, Brazil-
Descrição: dc.descriptionUniv Fed Jatai, Unidade Acad Ciencias Exatas & Tecnol, Campus Jatoba, BR-75801615 Jatai, GO, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Inst Quim, Dept Bioquim & Quim Organ, Lab Quim Med Sintese Organ & Modelagem Mol LaQMed, BR-14800060 Araraquara, SP, Brazil-
Formato: dc.format20-
Idioma: dc.languageen-
Publicador: dc.publisherSoc Brasileira Quimica-
Relação: dc.relationQuimica Nova-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectAChE inhibitors-
Palavras-chave: dc.subjectBuChE inhibitors-
Palavras-chave: dc.subjectAlzheimer's disease-
Palavras-chave: dc.subjectbioactive natural products-
Palavras-chave: dc.subjectsynthetic derivatives-
Título: dc.titleANTI-ALZHEIMER ACTIVITY OF SUBSTANCES FROM NATURAL PRODUCTS AND OF SYNTHETIC ORIGIN: SOME IMPORTANT EXAMPLES OF THE LAST 20 YEARS.-
Aparece nas coleções:Repositório Institucional - Unesp

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