Role of Iron Phthalocyanine Coordination in Catecholamines Detection

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorMartin, Cibely S. [UNESP]-
Autor(es): dc.creatorRubira, Rafael J. G. [UNESP]-
Autor(es): dc.creatorSilva, Jaqueline N. [UNESP]-
Autor(es): dc.creatorAlessio, Priscila [UNESP]-
Data de aceite: dc.date.accessioned2022-08-04T21:59:08Z-
Data de disponibilização: dc.date.available2022-08-04T21:59:08Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2021-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/surfaces4040027-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/218758-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/218758-
Descrição: dc.descriptionCatecholamines are an important class of neurotransmitters responsible for regularizing, controlling, and treating neural diseases. Based on control and diseases treatment, the development of methodology and dives to sensing is a promissory technology area. This work evaluated the role of iron phthalocyanine coordination (FePc) with the specific groups from catecholamine molecules (L-dopa, dopamine, epinephrine, and the amino acid tyrosine) and the effect of this coordination on electrochemical behavior. The in situ coordination analysis was performed through isotherms pi-A of FePc Langmuir films in the absence and presence of catecholamines. The pi-A isotherm indicates a strong interaction between FePc monolayer and L-Dopa and DA, which present a catechol group and a side chain with a protonated amino group (-NH3+). These strong interactions with catechol and amine groups were confirmed by characterization at the molecular level using the surface-enhanced Raman spectroscopy (SERS) from a Langmuir-Schaefer monolayer deposited onto Ag surfaces. The electrochemical measurements present a similar tendency, with lower oxidation potential observed to DA>L-Dopa>Ep. The results corroborate that the coordination of the analyte on the electron mediator surface plays an essential role in an electrochemical sensing application. The FePc LS film was applied as a sensor in tablet drug samples, showing a uniformity of content of 96% for detecting active compounds present in the L-Dopa drug samples.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionNational Institute for Science and Technology on Organic Electronics (INEO)-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Sch Technol & Appl Sci, BR-19060080 Presidente Prudente, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ UNESP, Sch Technol & Appl Sci, BR-19060080 Presidente Prudente, SP, Brazil-
Descrição: dc.descriptionFAPESP: 2014/50869-6-
Descrição: dc.descriptionFAPESP: 2017/06534-8-
Descrição: dc.descriptionFAPESP: 2017/15019-0-
Descrição: dc.descriptionFAPESP: 2020/05423-0-
Descrição: dc.descriptionCNPq: 422163/2018-0-
Descrição: dc.descriptionCNPq: 304836/2018-4-
Descrição: dc.descriptionNational Institute for Science and Technology on Organic Electronics (INEO): 465572/2014-6-
Descrição: dc.description: CAPES 23038.000776/201754-
Formato: dc.format323-335-
Idioma: dc.languageen-
Publicador: dc.publisherMdpi-
Relação: dc.relationSurfaces-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectcatecholamines-
Palavras-chave: dc.subjectiron coordination-
Palavras-chave: dc.subjectphthalocyanines-
Palavras-chave: dc.subjectelectrochemical sensing-
Título: dc.titleRole of Iron Phthalocyanine Coordination in Catecholamines Detection-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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