Hematological and biochemical parameters of premature kids of goats subjected to different dexamethasone protocols

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniv Fed Juiz de Fora UFJF-
Autor(es): dc.contributorFundacao Educ Andradina-
Autor(es): dc.contributorCtr Univ Rio Preto UNIRP-
Autor(es): dc.contributorCtr Univ Ourinhos Unifio-
Autor(es): dc.creatorNarciso, Luis Gustavo [UNESP]-
Autor(es): dc.creatorAlcindo, Jefferson Ferreira-
Autor(es): dc.creatorBovino, Fernanda-
Autor(es): dc.creatorTrevizan, Juliane Teramachi-
Autor(es): dc.creatorVieira, Dielson da Silva [UNESP]-
Autor(es): dc.creatorMartins de Almeida, Breno Fernando-
Autor(es): dc.creatorBosco, Anelise Maria [UNESP]-
Autor(es): dc.creatorFormiga Feitosa, Francisco Leydson [UNESP]-
Data de aceite: dc.date.accessioned2022-08-04T21:59:00Z-
Data de disponibilização: dc.date.available2022-08-04T21:59:00Z-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2022-04-28-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/0103-8478cr20210278-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/218717-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/218717-
Descrição: dc.descriptionCorticosteroid therapy has been used for ruminants to allow lung maturation and the birth of premature babies. However, when considering laboratory analyses of these animals, very little data is available regarding hematological and biochemical patterns, especially for premature goats, and the effects of corticotherapy on these parameters are unknown. In this context, the objective of this study was to evaluate the hematological and biochemical parameters during the first hours of life of premature kids from goats subjected to different dexamethasone protocols. For this, the goats were divided into four groups: group I, goats that received 20 mg of dexamethasone at 139 days of gestation; group II, 2 mg of dexamethasone from the 133rd to 136th day of gestation, 4 mg from the 137th to 139th, and 20 mg on the 140th; group III, 16 mg of dexamethasone from the 139th day, with repeated doses every 12 h until elective surgery; and group IV, goats that received 4, 8, 16, and 20 mg of dexamethasone at 137, 138, 139, and 140 days of gestation, respectively. Blood samples were obtained at birth (T0h) and after 1 (T1h), 12 (T12h), 24 (T24h), and 48 h (T48h) of life for hemogram and serum biochemistry assessment of urea, creatinine, total protein (PT), and gamma-glutamyltransferase (GGT). PT levels and GGT activity were lower at birth in all groups and rose after colostrum ingestion. The creatinine values for all the experimental groups did not differ between T0h and T1h; however, they decreased in the subsequent moments. Except for group I, urea concentrations were higher at T48h than at T1h. The red blood cell, hemoglobin, hematocrit, and mean corpuscular hemoglobin counts decreased over time. The total leukocyte count behaved differently in different experimental groups, and was influenced by the levels of dexamethasone, mainly due to the change in the counts of segmented neutrophils and lymphocytes. It was concluded that significant changes in the hematological and biochemical parameters occur in the first hours of life of premature kids, and that the treatment of goats with dexamethasone can affect these parameters in a dose-dependent manner.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionUniv Estadual Paulista UNESP, Dept Clin Cirurgia & Reprod Anim, Fac Med Vet Aracatuba FMVA, Aracatuba, SP, Brazil-
Descrição: dc.descriptionUniv Fed Juiz de Fora UFJF, Dept Med Vet, Juiz De Fora, MG, Brazil-
Descrição: dc.descriptionFundacao Educ Andradina, Andradina, SP, Brazil-
Descrição: dc.descriptionCtr Univ Rio Preto UNIRP, Dept Reprod Anim, Sao Jose Do Rio Preto, SP, Brazil-
Descrição: dc.descriptionCtr Univ Ourinhos Unifio, Ourinhos, SP, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista UNESP, Dept Clin Cirurgia & Reprod Anim, Fac Med Vet Aracatuba FMVA, Aracatuba, SP, Brazil-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2013/22435-9-
Formato: dc.format10-
Idioma: dc.languageen-
Publicador: dc.publisherUniv Federal Santa Maria-
Relação: dc.relationCiencia Rural-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectbiochemistry-
Palavras-chave: dc.subjectgoats-
Palavras-chave: dc.subjectcorticotherapy-
Palavras-chave: dc.subjecthematology-
Palavras-chave: dc.subjectearly parturition-
Título: dc.titleHematological and biochemical parameters of premature kids of goats subjected to different dexamethasone protocols-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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