An evaluation by rat colon anastomosis of the efficacy of fibrin glue derived from snake venom

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorLeite, C.v.s. [UNESP]-
Autor(es): dc.creatorNaresse, L.e. [UNESP]-
Autor(es): dc.creatorArantes, H.l.-
Autor(es): dc.creatorLopes, A.f.-
Autor(es): dc.creatorThomazini-santos, I.a. [UNESP]-
Autor(es): dc.creatorGiannini, M.j.s [UNESP]-
Autor(es): dc.creatorMercadante, M.c. [UNESP]-
Autor(es): dc.creatorBarraviera, B. [UNESP]-
Autor(es): dc.creatorKobayasi, S. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T01:13:03Z-
Data de disponibilização: dc.date.available2022-02-22T01:13:03Z-
Data de envio: dc.date.issued2021-07-14-
Data de envio: dc.date.issued2021-07-14-
Data de envio: dc.date.issued2000-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S0104-79302000000200004-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/212341-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/212341-
Descrição: dc.descriptionThe objective of this study was to evaluate the efficacy of fibrin adhesive made up of snake venom and bubaline fibrinogen by rat colon anastomosis. Eighty rats were randomly assigned into 2 experimental groups: GI control (anastomosis with extramucous interrupted suture) and GII (repair suture + fibrin glue). The animals were studied at the following 4 times: T0 – preoperative, T1 – 7th day postoperative, T2 – 14th day postoperative, and T3 – 21 st day postoperative. The macroscopic characteristics of the intestinal segment open and closed anastomosis and the bursting strength of the anastomosed segments were observed at each of the above times. The results showed that the anastomosed segments coapted and there was no difference in the bursting strength values between the 2 groups. There was a decrease in the bursting strength values up until the 7 th day postoperative in both groups with its progressive increase at the other times. Although important experimental studies using large animals are needed for a better evaluation of tissue repair processes, this adhesive may become a valuable tool for use in anastomosis.-
Descrição: dc.descriptionUniversidade Estadual Paulista, Botucatu School of Medicine (FMB)-
Descrição: dc.descriptionUniversidade Estadual Paulista, Center for the Study of Venoms and Venomous Animals - CEVAP-
Descrição: dc.descriptionUniversidade Estadual Paulista, School of Pharmaceutical Sciences of Araraquara-
Descrição: dc.descriptionUniversidade Estadual Paulista, Botucatu School of Medicine (FMB)-
Descrição: dc.descriptionUniversidade Estadual Paulista, Center for the Study of Venoms and Venomous Animals - CEVAP-
Descrição: dc.descriptionUniversidade Estadual Paulista, School of Pharmaceutical Sciences of Araraquara-
Formato: dc.format180-193-
Idioma: dc.languageen-
Publicador: dc.publisherCentro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP-
Relação: dc.relationJournal of Venomous Animals and Toxins-
Direitos: dc.rightsAcesso aberto-
???dc.source???: dc.sourceSciELO-
Palavras-chave: dc.subjectFibrin glue-
Palavras-chave: dc.subjectexperimental healing-
Palavras-chave: dc.subjectbursting strength-
Palavras-chave: dc.subjectexperimental anastomosis-
Palavras-chave: dc.subjectsnake venom-
Palavras-chave: dc.subjectcolon anastomosis-
Título: dc.titleAn evaluation by rat colon anastomosis of the efficacy of fibrin glue derived from snake venom-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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