An updated Axiom buffalo genotyping array map and mapping of cattle quantitative trait loci to the new water buffalo reference genome assembly

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorMichigan State Univ-
Autor(es): dc.contributorUniv Guelph-
Autor(es): dc.contributorUniv Maryland-
Autor(es): dc.creatorNascimento, A. V. [UNESP]-
Autor(es): dc.creatorRomero, A. R. S. [UNESP]-
Autor(es): dc.creatorNawaz, M. Y.-
Autor(es): dc.creatorCardoso, D. F.-
Autor(es): dc.creatorSantos, D. J. A.-
Autor(es): dc.creatorGondro, C.-
Autor(es): dc.creatorTonhati, H. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T01:08:14Z-
Data de disponibilização: dc.date.available2022-02-22T01:08:14Z-
Data de envio: dc.date.issued2021-06-26-
Data de envio: dc.date.issued2021-06-26-
Data de envio: dc.date.issued2021-06-09-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/age.13103-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/210810-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/210810-
Descrição: dc.descriptionThe objectives of this study were to provide the buffalo research community with an updated SNP map for the Axiom Buffalo Genotyping (ABG) array with genomic positions for SNP currently unmapped and to map all cattle QTL from the CattleQTLdb onto the buffalo reference assembly. To update the ABG array map, all SNP probe sequences from the ABG array were re-aligned against the UOA_WB_1 assembly. With the new map, the number of mapped markers increased by approximately 10% and went from 106 778 to 116 708, which reduced the average marker spacing by approximately 2 kb. A comparison of results between signatures of autozygosity study using the ABG and the new map showed that, when the additional markers were used there was an increase in the autozygosity peaks and additional peaks in BBU5 and BBU11 could be identified. After sequence alignment and quality control, 64 650 (UMD3.1) and 76 530 (ARS_UCD1.2) cattle QTL were mapped onto the buffalo genome. The mapping of the bovine QTL database onto the buffalo genome should be useful for genome-wide association studies in buffalo and, given the high homology between the two species, the positions of cattle QTL on the buffalo genome can serve as a stepping stone towards a water buffalo QTL database.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSao Paulo State Univ, Dept Anim Sci, BR-14884900 Jaboticabal, Brazil-
Descrição: dc.descriptionMichigan State Univ, Genet & Genome Sci Program, E Lansing, MI 48823 USA-
Descrição: dc.descriptionUniv Guelph, Dept Anim Biosci, Guelph, ON N1G 2W1, Canada-
Descrição: dc.descriptionUniv Maryland, Dept Anim Sci, College Pk, MD 20740 USA-
Descrição: dc.descriptionMichigan State Univ, Dept Anim Sci, E Lansing, MI 48823 USA-
Descrição: dc.descriptionSao Paulo State Univ, Dept Anim Sci, BR-14884900 Jaboticabal, Brazil-
Descrição: dc.descriptionFAPESP: 2016/21213-0-
Descrição: dc.descriptionFAPESP: 2017/10542-6-
Descrição: dc.descriptionFAPESP: 2018/25725-1-
Formato: dc.format4-
Idioma: dc.languageen-
Publicador: dc.publisherWiley-Blackwell-
Relação: dc.relationAnimal Genetics-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectBubalus bubalis-
Palavras-chave: dc.subjectdairy buffalo-
Palavras-chave: dc.subjectQTL map-
Palavras-chave: dc.subjectruns of homozygosity-
Palavras-chave: dc.subjectSNP map-
Título: dc.titleAn updated Axiom buffalo genotyping array map and mapping of cattle quantitative trait loci to the new water buffalo reference genome assembly-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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