Multiple endpoints of polylactic acid biomicroplastic toxicity in adult zebrafish (Danio rerio)

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorGoiano Fed Univ-
Autor(es): dc.contributorGoiano Fed Inst-
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorFed Univ Jatai-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Federal de Goiás (UFG)-
Autor(es): dc.creatorChagas, Thales Quintao-
Autor(es): dc.creatorFreitas, Italo Nascimento-
Autor(es): dc.creatorMontalvao, Mateus Flores-
Autor(es): dc.creatorNobrega, Rafael Henrique [UNESP]-
Autor(es): dc.creatorFerreira Machado, Monica Rodrigues-
Autor(es): dc.creatorCharlie-Silva, Ives-
Autor(es): dc.creatorCosta Araujo, Amanda Pereira da-
Autor(es): dc.creatorBatista Guimaraes, Abraao Tiago-
Autor(es): dc.creatorSilva Alvarez, Tenilce Gabriela da-
Autor(es): dc.creatorMalafaia, Guilherme-
Data de aceite: dc.date.accessioned2022-02-22T00:59:29Z-
Data de disponibilização: dc.date.available2022-02-22T00:59:29Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-08-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.chemosphere.2021.130279-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/210315-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/210315-
Descrição: dc.descriptionAlthough the toxicity of conventional microplastic types (i.e., petroleum derivatives) in different organisms is already known, knowledge about the effects of alternative biopolymers on aquatic vertebrates remains incipient. Thus, the aim of the present study is to test the hypothesis that the exposure of adult Danio rerio individuals to this pollutant for 30 days is enough to cause polylactic acid biomicroplastics (BioMPs of PLA) accumulation in their bodies, which leads to behavioral/neurotoxic, biochemical, and morphological changes. Based on our results, PLA BioMPs at concentrations of 2.5 and 5 mg/L accumulated in the liver, brain, gills and carcass of the assessed animals. However, such an accumulation was not able to cause locomotor damages or to trigger anxiety-like behavior in them. On the other hand, it was enough to cause behavioral changes (in shoal) predictive of co-specific social interaction and antipredatory defensive response deficit likely related to cholinergic changes inferred by increased acetylcholinesterase activity and REDOX imbalance. This imbalance was featured by increased production of reactive species. We observed that the treatments have affected animals' pigmentation pattern. Therefore, our study highlights the toxicological potential of the herein assessed biopolymer, and this finding puts in check the innocuousness of this material, as well as expands our knowledge about how PLA BioMPs can affect the ichthyofauna in freshwater environments. (C) 2021 Elsevier Ltd. All rights reserved.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionGoiano Federal Institute-
Descrição: dc.descriptionGoiano Fed Univ, Postgrad Program Cerrado Nat Resources Conservat, Urutai Campus, Urutai, Brazil-
Descrição: dc.descriptionGoiano Fed Inst, Biol Res Lab, Urutai Campus, Urutai, Brazil-
Descrição: dc.descriptionUniv Fed Uberlandia, Postgrad Program Ecol & Nat Resources Conservat, Uberlandia, MG, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Morphol Dept, Reprod & Mol Biol Grp, Botucatu, SP, Brazil-
Descrição: dc.descriptionFed Univ Jatai, Dept Biol Sci, Zebrafish Res & Reprod Lab LABFISH, Jatai, Brazil-
Descrição: dc.descriptionUniv Sao Paulo, Inst Biomed Sci, Dept Pharmacol, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Fed Goias, Postgrad Program Biotechnol & Biodivers, Goiania, Go, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Morphol Dept, Reprod & Mol Biol Grp, Botucatu, SP, Brazil-
Descrição: dc.descriptionCNPq: 426531/2018-3-
Descrição: dc.descriptionGoiano Federal Institute: 23219.001551.2020-92-
Formato: dc.format16-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationChemosphere-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectBiopolymers-
Palavras-chave: dc.subjectBiomicroplastics-
Palavras-chave: dc.subjectFish-
Palavras-chave: dc.subjectBehavioral toxicology-
Título: dc.titleMultiple endpoints of polylactic acid biomicroplastic toxicity in adult zebrafish (Danio rerio)-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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