Higher Prevalence of Extended-Spectrum Cephalosporin-Resistant Enterobacterales in Dogs Attended for Enteric Viruses in Brazil Before and After Treatment with Cephalosporins

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorMillennium Initiat Collaborat Res Bacterial Resis-
Autor(es): dc.contributorPontificia Univ Catolica Chile-
Autor(es): dc.contributorUniv Cayetano Heredia Peru-
Autor(es): dc.contributorUniv Desarrollo-
Autor(es): dc.contributorUniv Andres Bello-
Autor(es): dc.creatorSalgado-Caxito, Marilia [UNESP]-
Autor(es): dc.creatorMoreno-Switt, Andrea I.-
Autor(es): dc.creatorPaes, Antonio Carlos [UNESP]-
Autor(es): dc.creatorShiva, Carlos-
Autor(es): dc.creatorMunita, Jose M.-
Autor(es): dc.creatorRivas, Lina-
Autor(es): dc.creatorBenavides, Julio A.-
Data de aceite: dc.date.accessioned2022-02-22T00:58:27Z-
Data de disponibilização: dc.date.available2022-02-22T00:58:27Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/antibiotics10020122-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/210073-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/210073-
Descrição: dc.descriptionThe extensive use of antibiotics is a leading cause for the emergence and spread of antimicrobial resistance (AMR) among dogs. However, the impact of using antibiotics to treat viral infections on AMR remains unknown. In this study, we compared the prevalence of extended-spectrum cephalosporin-resistant Enterobacterales (ESCR-E) between dogs with a suspected infection of canine parvovirus (CPV) and canine distemper (CDV) before and after treatment with third-generation cephalosporins. We found a higher prevalence of ESCR-E faecal carriage in dogs suspected of CPV (37%) and CDV (15%) compared to dogs with noninfectious pathologies (9%) even prior to the start of their treatment. A 7-day course of ceftriaxone or ceftiofur administrated to CPV and CDV-suspected dogs substantially increased their ESCR-E faecal carriage during treatment (85% for CPV and 57% for CDV), and 4 weeks after the treatment ended (89% for CPV and 60% for CDV) when dogs were back in their households. Most of the observed resistance was carried by ESCR-E. coli carrying bla(CTX-M) genes. Our results suggest the need to optimize prophylactic antibiotic therapy in dogs treated for a suspected viral infection to prevent ESCR-E emergence and spread in the community.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFONDECYT-
Descrição: dc.descriptionNational Agency for Research and Development (ANID) FONDECYT Iniciacion-
Descrição: dc.descriptionANID Millennium Science Initiative/Millennium Initiative for Collaborative Research on Bacterial Resistance, MICROB-R-
Descrição: dc.descriptionSao Paulo State Univ, Sch Vet Med & Anim Sci, Dept Anim Prod & Prevent Vet Med, BR-18618000 Botucatu, SP, Brazil-
Descrição: dc.descriptionMillennium Initiat Collaborat Res Bacterial Resis, Santiago 7550000, Chile-
Descrição: dc.descriptionPontificia Univ Catolica Chile, Escuela Med Vet, Santiago 8940000, Chile-
Descrição: dc.descriptionUniv Cayetano Heredia Peru, Fac Vet Med & Zootech, Lima 15102, Peru-
Descrição: dc.descriptionUniv Desarrollo, Fac Med Clin Alemana, Genom & Resistant Microbes Grp, Santiago 7550000, Chile-
Descrição: dc.descriptionUniv Andres Bello, Fac Ciencias Vida, Dept Ecol & Biodiversidad, Santiago 8320000, Chile-
Descrição: dc.descriptionUniv Andres Bello, Fac Ciencias Vida, Ctr Invest Sustentabilidad, Santiago 8320000, Chile-
Descrição: dc.descriptionSao Paulo State Univ, Sch Vet Med & Anim Sci, Dept Anim Prod & Prevent Vet Med, BR-18618000 Botucatu, SP, Brazil-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFONDECYT: 1181167-
Descrição: dc.descriptionNational Agency for Research and Development (ANID) FONDECYT Iniciacion: 11181017-
Descrição: dc.descriptionANID Millennium Science Initiative/Millennium Initiative for Collaborative Research on Bacterial Resistance, MICROB-R: NCN17_081-
Formato: dc.format13-
Idioma: dc.languageen-
Publicador: dc.publisherMdpi-
Relação: dc.relationAntibiotics-basel-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectantimicrobial resistance-
Palavras-chave: dc.subjectantimicrobial prophylaxis-
Palavras-chave: dc.subjectcanine distemper-
Palavras-chave: dc.subjectcanine parvovirus-
Palavras-chave: dc.subjectcompanion animals-
Título: dc.titleHigher Prevalence of Extended-Spectrum Cephalosporin-Resistant Enterobacterales in Dogs Attended for Enteric Viruses in Brazil Before and After Treatment with Cephalosporins-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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