Characterization of Optimized TiO2 Nanotubes Morphology for Medical Implants: Biological Activity and Corrosion Resistance

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorKhalifa Univ Sci & Technol-
Autor(es): dc.contributorUniv Grenoble Alpes-
Autor(es): dc.contributorFed Inst Educ Sci & Technol Piaui-
Autor(es): dc.contributorUFPI Fed Univ Piaui-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniv Fed Piaui-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.creatorNogueira, Ricardo Pereira-
Autor(es): dc.creatorUchoa, Jose Deuzimar-
Autor(es): dc.creatorHilario, Fanny-
Autor(es): dc.creatorSantana-Melo, Gabriela de Fatima [UNESP]-
Autor(es): dc.creatorReis de Vasconcellos, Luana Marotta [UNESP]-
Autor(es): dc.creatorMarciano, Fernanda Roberta-
Autor(es): dc.creatorRoche, Virginie-
Autor(es): dc.creatorJorge Junior, Alberto Moreira-
Autor(es): dc.creatorLobo, Anderson Oliveira-
Data de aceite: dc.date.accessioned2022-02-22T00:58:06Z-
Data de disponibilização: dc.date.available2022-02-22T00:58:06Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.2147/IJN.S285805-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/209964-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/209964-
Descrição: dc.descriptionBackground: Nanostructured surface modifications of Ti-based biomaterials are moving up from a highly-promising to a successfully-implemented approach to developing safe and reliable implants. Methods: The study's main objective is to help consolidate the knowledge and identify the more suitable experimental strategies related to TiO2 nanotubes-modified surfaces. In this sense, it proposes the thorough investigation of two optimized nanotubes morphologies in terms of their biological activity (cell cytotoxicity, alkaline phosphatase activity, alizarin red mineralization test, and cellular adhesion) and their electrochemical behavior in simulated body fluid (SBF) electrolyte. Layers of small-short and large-long nanotubes were prepared and investigated in their amorphous and crystallized states and compared to non-anodized samples. Results: Results show that much more than the surface area development associated with the nanotubes' growth; it is the heat treatment-induced change from amorphous to crystalline anatase-rutile structures that ensure enhanced biological activity coupled to high corrosion resistance. Conclusion: Compared to both non-anodized and amorphous nanotubes layers, the crystallized nano-structures' outstanding bioactivity was related to the remarkable increase in their hydrophilic behavior, while the enhanced electrochemical stability was ascribed to the thickening of the dense ruble barrier layer at the Ti surface beneath the nanotubes.-
Descrição: dc.descriptionFrench Committee for the Evaluation of Academic and Scientific Cooperation with Brazil (COFECUB)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionKhalifa Univ Sci & Technol, Chem Engn Dept, Abu Dhabi 127788, U Arab Emirates-
Descrição: dc.descriptionUniv Grenoble Alpes, Univ Savoie Mt Blanc, GrenoblelNP LEPMI, CNRS, F-38000 Grenoble, France-
Descrição: dc.descriptionFed Inst Educ Sci & Technol Piaui, BR-64053390 Teresina, Brazil-
Descrição: dc.descriptionUFPI Fed Univ Piaui, Interdisciplinary Lab Adv Mat, BioMatLab Grp, Mat Sci & Engn Grad Program, BR-64049550 Teresina, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Dept Biosci & Oral Diag, Inst Sci & Technol, BR-12245000 Sao Jose Dos Campos, Brazil-
Descrição: dc.descriptionUniv Fed Piaui, Dept Phys, BR-64049550 Teresina, Brazil-
Descrição: dc.descriptionUniv Fed Sao Carlos, Dept Mat Engn, BR-13565905 Sao Carlos, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Dept Biosci & Oral Diag, Inst Sci & Technol, BR-12245000 Sao Jose Dos Campos, Brazil-
Descrição: dc.descriptionCAPES: 88887.321581/2019-00-
Descrição: dc.descriptionFAPESP: 2012/13179-6-
Descrição: dc.descriptionCNPq: 311531/2020-2-
Descrição: dc.descriptionCNPq: 301429/2017-0-
Descrição: dc.descriptionCNPq: 409847/2016-0-
Descrição: dc.descriptionCNPq: 310883/2020-2-
Descrição: dc.descriptionCNPq: 404683/2018-5-
Formato: dc.format667-682-
Idioma: dc.languageen-
Publicador: dc.publisherDove Medical Press Ltd-
Relação: dc.relationInternational Journal Of Nanomedicine-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectsurface modification-
Palavras-chave: dc.subjectTiO2 nanotubes-
Palavras-chave: dc.subjectcommercially pure titanium-
Palavras-chave: dc.subjectbioactivity-
Título: dc.titleCharacterization of Optimized TiO2 Nanotubes Morphology for Medical Implants: Biological Activity and Corrosion Resistance-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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