Preliminary assessment of electrochemotherapy feasibility in dogs with vesical transitional cell carcinoma

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorPetClin Clin-
Autor(es): dc.contributorBotucatu Vet Hosp-
Autor(es): dc.contributorPaulista Univ UNIP-
Autor(es): dc.contributorBiopulse Ltd-
Autor(es): dc.creatorDos Anjos, Denner Santos [UNESP]-
Autor(es): dc.creatorBuosi, Rafaela Guedes-
Autor(es): dc.creatorRoratto, Isadora-
Autor(es): dc.creatorMesquita, Luciane dos Reis [UNESP]-
Autor(es): dc.creatorSierra Matiz, Oscar Rodrigo [UNESP]-
Autor(es): dc.creatorFonseca-Alves, Carlos Eduardo [UNESP]-
Autor(es): dc.creatorSpugnini, Enrico Pierluigi-
Data de aceite: dc.date.accessioned2022-02-22T00:57:20Z-
Data de disponibilização: dc.date.available2022-02-22T00:57:20Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.30466/vrf.2020.113009.2688-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/209678-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/209678-
Descrição: dc.descriptionElectroporation is a technique that increases the uptake of chemotherapeutic drugs by tumors. Electrochemotherapy (ECT) has been successfully used to treat solid tumors. Recently, novel applications have been explored in the treatment of visceral tumors. This report aimed to describe the ECT as an approach to vesical carcinoma in three dogs. The patients received ECT with bleomycin as an intravenous bolus and intra-lesional cisplatin (cases 2 and 3). The ECT was performed by electroporator (Onkodisruptor (R)) using a plate and/or a single pair needle array electrode. Case 1 was a 7-year-old female Pitbull dog with a history of hematuria and stranguria. The ECT was performed during cystotomy using a single pair array electrode. However, the patient developed uroabdomen two days post-ECT and died 5 days later. Case 2 was a 12-year-old female Poodle dog with hematuria, dysuria, and pollakiuria. Cystotomy and ECT were performed using plate array electrodes. Complete remission of the intra-luminal mass was observed 11 days post-ECT. However, 21 days after the procedure, an acute unilateral renal failure occurred possibly due to a neoplastic embolus into the right ureter leading to kidney hydronephrosis, and the patient was euthanized. Case 3 was a 10-year-old female Cocker dog with hematuria and pollakiuria. The patient was fully competent after ECT without clinical signs of pollakiuria and recovered from hematuria 7 days post-ECT. The bladder returned to normal status 28 days post-ECT. The ECT was not able to increase the overall survival of the patients evaluated and should be indicated carefully. (C) 2020 Urmia University. All rights reserved.-
Descrição: dc.descriptionSao Paulo State Univ, Dept Vet Clin & Surg, Jaboticabal, SP, Brazil-
Descrição: dc.descriptionPetClin Clin, Sao Paulo, Brazil-
Descrição: dc.descriptionBotucatu Vet Hosp, Sao Paulo, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Sch Vet Med & Anim Sci, Dept Vet Surg & Anesthesiol, Botucatu, SP, Brazil-
Descrição: dc.descriptionPaulista Univ UNIP, Inst Hlth Sci, Bauru, SP, Brazil-
Descrição: dc.descriptionBiopulse Ltd, Naples, Italy-
Descrição: dc.descriptionSao Paulo State Univ, Dept Vet Clin & Surg, Jaboticabal, SP, Brazil-
Descrição: dc.descriptionSao Paulo State Univ, Sch Vet Med & Anim Sci, Dept Vet Surg & Anesthesiol, Botucatu, SP, Brazil-
Formato: dc.format289-293-
Idioma: dc.languageen-
Publicador: dc.publisherUrmia Univ-
Relação: dc.relationVeterinary Research Forum-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectBleomycin-
Palavras-chave: dc.subjectElectroporation-
Palavras-chave: dc.subjectIntra-operative electrochemotherapy-
Palavras-chave: dc.subjectTransitional cell carcinoma-
Palavras-chave: dc.subjectVisceral tumors-
Título: dc.titlePreliminary assessment of electrochemotherapy feasibility in dogs with vesical transitional cell carcinoma-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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