Collagen I and III Ratios and Tenacity of Rats' Muscle Injured and Treated with Platelet-Rich Plasma

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniv Oeste Paulista-
Autor(es): dc.creatorGarcia, Thiago Alves-
Autor(es): dc.creatorTamura Ozaki, Guilherme Akio [UNESP]-
Autor(es): dc.creatorCastoldi, Robson Chacon-
Autor(es): dc.creatorJob, Aldo Eloizo [UNESP]-
Autor(es): dc.creatorTrindade Camargo, Regina Celi [UNESP]-
Autor(es): dc.creatorSilva Camargo Filho, Jose Carlos [UNESP]-
Autor(es): dc.creatorBelangero, William Dias-
Data de aceite: dc.date.accessioned2022-02-22T00:56:31Z-
Data de disponibilização: dc.date.available2022-02-22T00:56:31Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-10-01-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/209433-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/209433-
Descrição: dc.descriptionSevere muscle injuries are common in accidents and have a delayed recovery of muscle integrity. In these cases, muscle suture surgery is the standard treatment. However, Platelet Rich Plasma (PRP), has been widely used in orthopedic injuries due to its growth factors. Thus, the objective of the study will be to analyze the association of suture and PRP techniques in the collagen and tenacity of the injured muscle. Were used seventy rats, divided into five groups: control (C), injury control (CI), injury and suture (IS), injury and PRP (IP), injury, suture, and PRP (ISP). Were sectioned approximately 50 % of the width and 100 % of the thickness of the gastrocnemius muscle. The homologous PRP was applied 24h after the injury. On the 7th day after the injury, the animals were euthanized and their muscles subjected to mechanical testing to measure tenacity or collagen analysis to calculate the ratio between type I and III collagen. The results show a significant decrease (p <0.05) in the values of the relationship between collagens in all injured groups (CI, IS, IP, ISP) compared to group C. In injured groups, the tenacity was significantly (p <0.05) reduced compared to the control group, with no observed difference between treatments and injured groups. The amount of collagen in the injured area has increased, but it did not affect the tenacity of the muscles, which was reduced.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionUniversidade do Oeste Paulista (Unoeste)-
Descrição: dc.descriptionUniv Estadual Campinas, Fac Ciencias Med, Ctr Med Expt & Cirurgia, Lab Biomat LABIMO, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista UNIP, Dept Fisioterapia, Campus Aracatuba, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Oeste Paulista, Dept Educ Fis, Campus Presidente Prudente, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Dept Fis, Campus Presidente Prudente, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Dept Fisioterapia, Campus Presidente Prudente, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Campinas, Fac Ciencias, Dept Ortopedia & Traumatol, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista UNIP, Dept Fisioterapia, Campus Aracatuba, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Dept Fis, Campus Presidente Prudente, Sao Paulo, Brazil-
Descrição: dc.descriptionUniv Estadual Paulista, Dept Fisioterapia, Campus Presidente Prudente, Sao Paulo, Brazil-
Descrição: dc.descriptionFAPESP: 2017/06930-0-
Formato: dc.format1392-1397-
Idioma: dc.languageen-
Publicador: dc.publisherSoc Chilena Anatomia-
Relação: dc.relationInternational Journal Of Morphology-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectMuscle injury-
Palavras-chave: dc.subjectPlatelet-rich plasma-
Palavras-chave: dc.subjectSuture-
Palavras-chave: dc.subjectCollagen-
Título: dc.titleCollagen I and III Ratios and Tenacity of Rats' Muscle Injured and Treated with Platelet-Rich Plasma-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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