Signatures of Selection in Composite Vrindavani Cattle of India

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorIndian Council Agr Res ICAR-
Autor(es): dc.contributorMichigan State Univ-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorSingh, Akansha-
Autor(es): dc.creatorMehrotra, Arnav-
Autor(es): dc.creatorGondro, Cedric-
Autor(es): dc.creatorRomero, Andrea Renata da Silva [UNESP]-
Autor(es): dc.creatorPandey, Ashwni Kumar-
Autor(es): dc.creatorKarthikeyan, A.-
Autor(es): dc.creatorBashir, Aamir-
Autor(es): dc.creatorMishra, B. P.-
Autor(es): dc.creatorDutt, Triveni-
Autor(es): dc.creatorKumar, Amit-
Data de aceite: dc.date.accessioned2022-02-22T00:55:15Z-
Data de disponibilização: dc.date.available2022-02-22T00:55:15Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-17-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3389/fgene.2020.589496-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/209058-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/209058-
Descrição: dc.descriptionVrindavani is an Indian composite cattle breed developed by crossbreeding taurine dairy breeds with native indicine cattle. The constituent breeds were selected for higher milk production and adaptation to the tropical climate. However, the selection response for production and adaptation traits in the Vrindavani genome is not explored. In this study, we provide the first overview of the selection signatures in the Vrindavani genome. A total of 96 Vrindavani cattle were genotyped using the BovineSNP50 BeadChip and the SNP genotype data of its constituent breeds were collected from a public database. Within-breed selection signatures in Vrindavani were investigated using the integrated haplotype score (iHS). The Vrindavani breed was also compared to each of its parental breeds to discover between-population signatures of selection using two approaches, cross-population extended haplotype homozygosity (XP-EHH) and fixation index (F-ST). We identified 11 common regions detected by more than one method harboring genes such as LRP1B, TNNI3K, APOB, CACNA2D1, FAM110B, and SPATA17 associated with production and adaptation. Overall, our results suggested stronger selective pressure on regions responsible for adaptation compared to milk yield.-
Descrição: dc.descriptionICMR fellowship-
Descrição: dc.descriptionIndian Council Agr Res ICAR, Indian Vet Res Inst, Anim Genet Div, Bareilly, Uttar Pradesh, India-
Descrição: dc.descriptionMichigan State Univ, Dept Anim Sci, E Lansing, MI 48824 USA-
Descrição: dc.descriptionSao Paulo State Univ, Dept Anim Sci, Sao Paulo, Brazil-
Descrição: dc.descriptionIndian Council Agr Res ICAR, Indian Vet Res Inst, Anim Biotechnol, Bareilly, Uttar Pradesh, India-
Descrição: dc.descriptionIndian Council Agr Res ICAR, Indian Vet Res Inst, Livestock Prod & Management, Bareilly, Uttar Pradesh, India-
Descrição: dc.descriptionSao Paulo State Univ, Dept Anim Sci, Sao Paulo, Brazil-
Formato: dc.format7-
Idioma: dc.languageen-
Publicador: dc.publisherFrontiers Media Sa-
Relação: dc.relationFrontiers In Genetics-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectcrossbred cattle-
Palavras-chave: dc.subjectF-ST-
Palavras-chave: dc.subjectintegrated haplotype score-
Palavras-chave: dc.subjectselection signature-
Palavras-chave: dc.subjectXP-EHH-
Título: dc.titleSignatures of Selection in Composite Vrindavani Cattle of India-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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