Metabolic profile and adipokine levels in overweight and obese dogs

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorState Univ Northern Parana-
Autor(es): dc.contributorUniv North Parana-
Autor(es): dc.contributorUniversidade Estadual de Londrina (UEL)-
Autor(es): dc.creatorDe Marchi, Paula Nassar [UNESP]-
Autor(es): dc.creatorAraujo Machado, Luiz Henrique de [UNESP]-
Autor(es): dc.creatorHolsback, Luciane-
Autor(es): dc.creatorCalesso, Jessica Ragazzi-
Autor(es): dc.creatorFagnani, Rafael-
Autor(es): dc.creatorZacarias Junior, Ademir-
Autor(es): dc.creatorLahm Cardoso, Mauro Jose-
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Descrição: dc.descriptionObesity in dogs is increasingly present in the veterinary practice. In humans, it is known that there is a significant correlation between obesity and the development of hypertension and insulin resistance (IR), a clinical picture called metabolic syndrome. In dogs, however, there are only anecdotes about the syndrome. The objectives of this study were to determine serum levels of adiponectin, leptin, triglycerides, cholesterol, insulin, glucose, homeostasis assessment of B cell function (HOMA-B), homeostasis assessment of insulin resistance (HOMA-IR), and systolic blood pressure (SBP) in dogs with different body conditions (BC) and body fat (BF) without endocrine disease. For this purpose, 76 healthy dogs were submitted to evaluation of body conditions score (BCS) and morphometry. The dogs were separated into 3 groups: optimal BC [BCS 3,4, or 5 of 9 and BF% of 13 to 27-Group 1 (G1)], overweight [BCS 6 and 7 of 9 and BF% of 14 to 38- Group 2 (G2)], obese [BCS 8 and 9 of 9 and BF% greater than or equal to 34-Group 3 (G3)]. G3 presented higher serum levels of total protein, triglycerides, glucose, insulin, and HOMA-IR. Adipokines did not correlate to any other parameter, but the occurrence of hyperinsulinemia was higher in G3. The results have shown that obese dogs presented IR and alterations in fat metabolism.-
Descrição: dc.descriptionAraucaria Foundation-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionPaulista State Univ Julio de Mesquita Filho, Coll Vet Med & Anim Sci, Botucatu, SP, Brazil-
Descrição: dc.descriptionState Univ Northern Parana, Coll Vet Med, Bandeirantes, Parana, Brazil-
Descrição: dc.descriptionUniv North Parana, Coll Prod Engn, Londrina, Parana, Brazil-
Descrição: dc.descriptionUniv Estadual Londrina, Agr Sci Ctr, Londrina, Parana, Brazil-
Descrição: dc.descriptionPaulista State Univ Julio de Mesquita Filho, Coll Vet Med & Anim Sci, Botucatu, SP, Brazil-
Descrição: dc.descriptionAraucaria Foundation: 931/2013-
Formato: dc.format1093-1099-
Idioma: dc.languageen-
Publicador: dc.publisherScientific Technical Research Council Turkey-tubitak-
Relação: dc.relationTurkish Journal Of Veterinary & Animal Sciences-
???dc.source???: dc.sourceWeb of Science-
Palavras-chave: dc.subjectAdipokines-
Palavras-chave: dc.subjectsystolic hypertension-
Palavras-chave: dc.subjectobesity-
Palavras-chave: dc.subjectinsulin resistance-
Título: dc.titleMetabolic profile and adipokine levels in overweight and obese dogs-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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