Highlights in poloxamer-based drug delivery systems as strategy at local application for vaginal infections

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.creatorCarvalho, Gabriela Corrêa [UNESP]-
Autor(es): dc.creatorAraujo, Victor Hugo Sousa [UNESP]-
Autor(es): dc.creatorFonseca-Santos, Bruno-
Autor(es): dc.creatorde Araújo, Jennifer Thayanne Cavalcante [UNESP]-
Autor(es): dc.creatorde Souza, Maurício Palmeira Chaves [UNESP]-
Autor(es): dc.creatorDuarte, Jonatas Lobato [UNESP]-
Autor(es): dc.creatorChorilli, Marlus [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:54:18Z-
Data de disponibilização: dc.date.available2022-02-22T00:54:18Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ijpharm.2021.120635-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208742-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208742-
Descrição: dc.descriptionInfectious diseases related to the vagina include diseases caused by the imbalance of the vaginal flora and by sexually transmitted infections. Some of these present themselves as a public health problem due to the lack of efficient treatment that leads to their complete cure, and others due to the growing resistance to drugs used in therapy. In this sense, new treatment strategies are desirable, with vaginal administration rout being a great choice since can bypass first-pass metabolism and decrease drug interactions and adverse effects. However, it is worth highlighting limitations related to patient's discomfort at application time. Thereby, the use of poloxamer-based drug delivery systems is desirable due its stimuli-sensitive characteristic. Therefore, the present review reports a brief overview of poloxamer properties, biological behavior and advances in poloxamer applications in controlled drug release systems for infectious diseases related to the vagina treatment and prevention.-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionFaculty of Pharmaceutical Sciences University of Campinas (UNICAMP)-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences São Paulo State University (UNESP)-
Formato: dc.format120635-
Idioma: dc.languageen-
Relação: dc.relationInternational journal of pharmaceutics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiological behavior-
Palavras-chave: dc.subjectDrug delivery-
Palavras-chave: dc.subjectInfectious diseases-
Palavras-chave: dc.subjectPoloxamer-
Palavras-chave: dc.subjectVaginal application-
Título: dc.titleHighlights in poloxamer-based drug delivery systems as strategy at local application for vaginal infections-
Aparece nas coleções:Repositório Institucional - Unesp

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