Aerobic Exercise Combined With Transcranial Direct Current Stimulation Over the Prefrontal Cortex in Parkinson Disease: Effects on Cortical Activity, Gait, and Cognition

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorOregon Health and Science University-
Autor(es): dc.contributorUniversidade Federal do ABC (UFABC)-
Autor(es): dc.creatorConceição, Núbia Ribeiro [UNESP]-
Autor(es): dc.creatorGobbi, Lilian Teresa Bucken [UNESP]-
Autor(es): dc.creatorNóbrega-Sousa, Priscila [UNESP]-
Autor(es): dc.creatorOrcioli-Silva, Diego [UNESP]-
Autor(es): dc.creatorBeretta, Victor Spiandor [UNESP]-
Autor(es): dc.creatorLirani-Silva, Ellen-
Autor(es): dc.creatorOkano, Alexandre Hideki-
Autor(es): dc.creatorVitório, Rodrigo [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:54:14Z-
Data de disponibilização: dc.date.available2022-02-22T00:54:14Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1177/15459683211019344-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208722-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208722-
Descrição: dc.descriptionBackground: Since people with Parkinson disease (PD) rely on limited prefrontal executive resources for the control of gait, interventions targeting the prefrontal cortex (PFC) may help in managing PD-related gait impairments. Transcranial direct current stimulation (tDCS) can be used to modulate PFC excitability and improve prefrontal cognitive functions and gait. Objective: We investigated the effects of adding anodal tDCS applied over the PFC to a session of aerobic exercise on gait, cognition, and PFC activity while walking in people with PD. Methods: A total of 20 people with PD participated in this randomized, double-blinded, sham-controlled crossover study. Participants attended two 30-minute sessions of aerobic exercise (cycling at moderate intensity) combined with different tDCS conditions (active- or sham-tDCS), 1 week apart. The order of sessions was counterbalanced across the sample. Anodal tDCS (2 mA for 20 minutes [active-tDCS] or 10 s [sham-tDCS]) targeted the PFC in the most affected hemisphere. Spatiotemporal gait parameters, cognitive functions, and PFC activity while walking were assessed before and immediately after each session. Results: Compared with the pre-assessment, participants decreased step time variability (effect size: −0.4), shortened simple and choice reaction times (effect sizes: −0.73 and −0.57, respectively), and increased PFC activity in the stimulated hemisphere while walking (effect size: 0.54) only after aerobic exercise + active-tDCS. Conclusion: The addition of anodal tDCS over the PFC to a session of aerobic exercise led to immediate positive effects on gait variability, processing speed, and executive control of walking in people with PD.-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Biosciences Graduate Program in Movement Sciences-
Descrição: dc.descriptionOregon Health and Science University Department of Neurology-
Descrição: dc.descriptionFederal University of ABC (UFABC) Center for Mathematics Computation and Cognition-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Biosciences Graduate Program in Movement Sciences-
Idioma: dc.languageen-
Relação: dc.relationNeurorehabilitation and Neural Repair-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectaerobic exercise-
Palavras-chave: dc.subjectcognition-
Palavras-chave: dc.subjectfNIRS-
Palavras-chave: dc.subjectgait-
Palavras-chave: dc.subjecttDCS-
Título: dc.titleAerobic Exercise Combined With Transcranial Direct Current Stimulation Over the Prefrontal Cortex in Parkinson Disease: Effects on Cortical Activity, Gait, and Cognition-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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