Biosimilar knowledge and viewpoints among Brazilian inflammatory bowel disease patients

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Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorBrazilian Crohn’s Disease and Ulcerative Colitis Association (Associação Brasileira de Colite Ulcerativa e Doença de Crohn: ABCD)-
Autor(es): dc.contributorGastrosaúde: IBD Clinic-
Autor(es): dc.contributorEuropean Federation of Crohn’s and Ulcerative Colitis Association (EFCCA)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorNancy University Hospital-
Autor(es): dc.creatorGarcia, Karoline Soares-
Autor(es): dc.creatorFacas, Bianca Pocopetz-
Autor(es): dc.creatorMachado, Marta Brenner-
Autor(es): dc.creatorTeixeira, Fábio Vieira-
Autor(es): dc.creatorAvedano, Luisa-
Autor(es): dc.creatorLönnfors, Sanna-
Autor(es): dc.creatorHossne, Rogério Saad [UNESP]-
Autor(es): dc.creatorPeyrin-Biroulet, Laurent-
Autor(es): dc.creatorQueiroz, Natália Sousa Freitas-
Data de aceite: dc.date.accessioned2022-02-22T00:54:07Z-
Data de disponibilização: dc.date.available2022-02-22T00:54:07Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1177/17562848211013249-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208691-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208691-
Descrição: dc.descriptionBackground: In this analysis we aimed to describe Brazilian inflammatory bowel disease (IBD) patients’ knowledge and perceptions regarding biosimilars and compare with viewpoints from non-Brazilian patients. Methods: An online survey consisting of 19 questions was made available by the European Federation of Crohn’s and Ulcerative Colitis Associations between July 2018 and December 2018. Only respondents who had heard of biosimilars were asked to respond to all of the questions. Results: A total of 102 Brazilian IBD patients responded to the survey. The majority (78.4%) of patients had been exposed to anti-tumor-necrosis-factor drugs and 63.4% of them had heard of biosimilars. Brazilian respondents worried significantly more about biosimilars being less effective than the originator (62.5% versus 47.9%, p value 0.03) and molecular differences between biosimilars and originators (53.1% versus 31.8, p value 0.001) as compared with non-Brazilian IBD patients. The majority of Brazilian (75%) and non-Brazilian (64.1%) respondents thought that the lower cost of biosimilars should not come before their safety and efficacy (p value 0.09). In addition, 79.1% of Brazilian respondents believed that the arrival of biosimilars will have an impact on the management of IBD. Conclusions: Brazilian patients reported higher rates of misconceptions regarding biosimilars than non-Brazilian IBD patients. Although patients still worry about different aspects regarding biosimilars, they also tend to be confident that biosimilars will have an impact on the management of their disease. With the recent approval of many biosimilars in Brazil and the imminent widespread use of these drugs, our data raise awareness for the need of providing patient education to prevent negative expectations toward switching to biosimilars.-
Descrição: dc.descriptionDepartment of Gastroenterology University of São Paulo School of Medicine, 255 Doutor Enéas de Carvalho Aguiar Avenue-
Descrição: dc.descriptionDepartment of Gastroenterology University of São Paulo School of Medicine-
Descrição: dc.descriptionDepartment of Gastroenterology Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) Brazilian Crohn’s Disease and Ulcerative Colitis Association (Associação Brasileira de Colite Ulcerativa e Doença de Crohn: ABCD)-
Descrição: dc.descriptionGastrosaúde: IBD Clinic-
Descrição: dc.descriptionEuropean Federation of Crohn’s and Ulcerative Colitis Association (EFCCA)-
Descrição: dc.descriptionPaulista State University (UNESP) Botucatu Medical School-
Descrição: dc.descriptionDepartment of Gastroenterology Nancy University Hospital-
Descrição: dc.descriptionPaulista State University (UNESP) Botucatu Medical School-
Idioma: dc.languageen-
Relação: dc.relationTherapeutic Advances in Gastroenterology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectadalimumab-
Palavras-chave: dc.subjectbiosimilar-
Palavras-chave: dc.subjectinflammatory bowel disease-
Palavras-chave: dc.subjectinfliximab-
Título: dc.titleBiosimilar knowledge and viewpoints among Brazilian inflammatory bowel disease patients-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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