Eco-friendly and inexpensive food grade bioethanol for Eugenia uniflora L. chromatographic fingerprinting: A trade-off between separation and sustainability

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorSouza, Otávio Aguiar [UNESP]-
Autor(es): dc.creatorFurlani, Rafael Pelegrino [UNESP]-
Autor(es): dc.creatorRamalhão, Vitória Giovanna da Silva [UNESP]-
Autor(es): dc.creatorBorges, Maiara Stefanini [UNESP]-
Autor(es): dc.creatorFunari, Cristiano Soleo [UNESP]-
Autor(es): dc.creatorBolzani, Vanderlan da Silva [UNESP]-
Autor(es): dc.creatorRinaldo, Daniel [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:53:58Z-
Data de disponibilização: dc.date.available2022-02-22T00:53:58Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.phytol.2021.04.010-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208633-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208633-
Descrição: dc.descriptionIn this work, we developed a green HPLC-PAD method to fingerprint Eugenia uniflora L. leaves by employing Design of Experiments with inexpensive food grade bioethanol as mobile-phase organic modifier aiming to cover Green Analytical Chemistry (GAC) principles and concepts. Initially, two different chromatographic columns coupled with five chromatographic factors were screened employing a Fractional Factorial Design. Once the phenyl-hexyl column was chosen and the most important factors were known, they were optimized in a Central Composite Design (CCD). Outcomes were monitored using two multiparametric responses: Green Chromatographic Fingerprinting Response (GCFR) with modifications and HPLC-EAT (Environmental Assessment Tool), and Derringer's desirability function was employed to reach a trade-off between them. The Response Surface Methodology (RSM) strategy enabled the prediction of the optimized chromatographic conditions as 5.26–52.63 % of the food grade bioethanol (95 °GL) in 30 min, at 35 °C, and 0.6 mL min−1. The simultaneous consideration of environmental and separation parameters led to the successful development of a validated HPLC-PAD method more efficient, cheaper, and almost 3-fold greener when compared with a preliminary reference method reported in the literature, also being applicable even by small laboratories without cutting-edge instrumentation.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionUNESP - São Paulo State University Institute of Chemistry, 55 Professor Francisco Degni, Quitandinha-
Descrição: dc.descriptionUNESP - São Paulo State University School of Agricultural Sciences, 1879 Doutor José Barbosa de Barros St., Jardim Paraíso-
Descrição: dc.descriptionUNESP - São Paulo State University School of Sciences, 14-01 Engenheiro Luiz Edmundo Carrijo Coube Ave., Vargem Limpa-
Descrição: dc.descriptionUNESP - São Paulo State University Institute of Chemistry, 55 Professor Francisco Degni, Quitandinha-
Descrição: dc.descriptionUNESP - São Paulo State University School of Agricultural Sciences, 1879 Doutor José Barbosa de Barros St., Jardim Paraíso-
Descrição: dc.descriptionUNESP - São Paulo State University School of Sciences, 14-01 Engenheiro Luiz Edmundo Carrijo Coube Ave., Vargem Limpa-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2014/50926-0-
Descrição: dc.descriptionFAPESP: 2016/08179-8-
Formato: dc.format200-207-
Idioma: dc.languageen-
Relação: dc.relationPhytochemistry Letters-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDerringer's desirability function-
Palavras-chave: dc.subjectGreen analytical chemistry-
Palavras-chave: dc.subjectGreen liquid chromatography-
Palavras-chave: dc.subjectHerbal fingerprint-
Palavras-chave: dc.subjectResponse surface methodology-
Título: dc.titleEco-friendly and inexpensive food grade bioethanol for Eugenia uniflora L. chromatographic fingerprinting: A trade-off between separation and sustainability-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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