Atenção: Todas as denúncias são sigilosas e sua identidade será preservada.
Os campos nome e e-mail são de preenchimento opcional
Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | University of Vale do Paraiba/UNIVAP | - |
Autor(es): dc.contributor | Photonics Division of Institute of Advanced Studies (EFO-IEAv) | - |
Autor(es): dc.creator | Terra-Garcia, Maíra [UNESP] | - |
Autor(es): dc.creator | de Souza, Cheyenne Marçal [UNESP] | - |
Autor(es): dc.creator | Ferreira Gonçalves, Nathalia Maria [UNESP] | - |
Autor(es): dc.creator | Pereira, André Henrique Correia | - |
Autor(es): dc.creator | de Barros, Patrícia Pimentel [UNESP] | - |
Autor(es): dc.creator | Borges, Alessandra Bühler [UNESP] | - |
Autor(es): dc.creator | Miyakawa, Walter | - |
Autor(es): dc.creator | Strixino, Juliana Ferreira | - |
Autor(es): dc.creator | Junqueira, Juliana Campos [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:53:55Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:53:55Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-01 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.pdpdt.2021.102303 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/208619 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/208619 | - |
Descrição: dc.description | Photodynamic therapy (PDT) is a promising strategy to control cariogenic pathogens, such as Streptococcus mutans. Seeking to reach the total bacterial elimination from dental surfaces, novel photosensitizers have been investigated, such as Fotoenticine (FTC) derived from chlorin e6. The objective of this study was to investigate the photodynamic effects of FTC against several clinical strains of S. mutans. Clinical isolates were obtained from patients with active carious lesions, identified by molecular analysis and subjected to PDT using laser irradiation (660 nm and 39.5 J/cm2) in planktonic and biofilm stages. We identified 11 S. mutans strains from cervical, occlusal and proximal caries. PDT mediated by FTC has totally eliminated the S. mutans cells in planktonic growth for all analyzed strains. In biofilms, PDT with FTC reached statistically significant reductions compared with the non-treated control group, at 5.4, 5.5 and 6.5 Log10 (CFU/mL), respectively, for the strains from proximal, occlusal and cervical caries. The scanning electron microscopy evaluations confirmed that PDT mediated by FTC was able to disaggregate and kill the S. mutans cells adhered to enamel surface, suggesting its potential to disinfect the dental tissues. | - |
Descrição: dc.description | Department of Biosciences and Oral Diagnosis Institute of Science and Technology São Paulo State University/UNESP | - |
Descrição: dc.description | Photobiology Applied to Health Research and Development Institute IP&D University of Vale do Paraiba/UNIVAP | - |
Descrição: dc.description | Department of Restorative Dentistry Institute of Science and Technology São Paulo State University/UNESP | - |
Descrição: dc.description | Photonics Division of Institute of Advanced Studies (EFO-IEAv) | - |
Descrição: dc.description | Department of Biosciences and Oral Diagnosis Institute of Science and Technology São Paulo State University/UNESP | - |
Descrição: dc.description | Department of Restorative Dentistry Institute of Science and Technology São Paulo State University/UNESP | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Photodiagnosis and Photodynamic Therapy | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Dental caries | - |
Palavras-chave: dc.subject | Fotoenticine | - |
Palavras-chave: dc.subject | Photodynamic therapy | - |
Palavras-chave: dc.subject | Streptococcus mutans | - |
Título: dc.title | Antimicrobial effects of photodynamic therapy with Fotoenticine on Streptococcus mutans isolated from dental caries | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
O Portal eduCAPES é oferecido ao usuário, condicionado à aceitação dos termos, condições e avisos contidos aqui e sem modificações. A CAPES poderá modificar o conteúdo ou formato deste site ou acabar com a sua operação ou suas ferramentas a seu critério único e sem aviso prévio. Ao acessar este portal, você, usuário pessoa física ou jurídica, se declara compreender e aceitar as condições aqui estabelecidas, da seguinte forma: