Development of a New Electrochemical Sensor Based on Mag-MIP Selective Toward Amoxicillin in Different Samples

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorNational University of Engineering-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorToxicological Evaluation Removal of Micropollutants and Radioactives (INCT-DATREM)-
Autor(es): dc.creatorLópez, Rosario-
Autor(es): dc.creatorKhan, Sabir [UNESP]-
Autor(es): dc.creatorWong, Ademar [UNESP]-
Autor(es): dc.creatorSotomayor, María del Pilar Taboada [UNESP]-
Autor(es): dc.creatorPicasso, Gino-
Data de aceite: dc.date.accessioned2022-02-22T00:53:44Z-
Data de disponibilização: dc.date.available2022-02-22T00:53:44Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-03-19-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3389/fchem.2021.615602-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208557-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208557-
Descrição: dc.descriptionThis work describes an electrochemical sensor for the selective recognition and quantification of amoxicillin and a β-lactam antibiotic in real samples. This sensor consists of a carbon paste electrode (CPE) modified with mag-MIP (magnetic molecularly imprinted polymer), which was prepared by precipitation method via free radical using acrylamide (AAm) as functional monomer, N,N′-methylenebisacrylamide (MBAA) as a crosslinker, and potassium persulfate (KPS) as initiator, to functionalized magnetic nanoparticles. The magnetic non-imprinted polymers (mag-NIP) were prepared using the same experimental procedure without analyte and used for the preparation of a CPE for comparative studies. The morphological, structural, and electrochemical characteristics of the nanostructured material were evaluated using Field emission gun scanning electron microscopy (FEG-SEM), Transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), Vibrating sample magnetometry (VSM), X-ray diffraction (XRD), and voltammetric technique. Electrochemical experiments performed by square wave voltammetry show that the mag-MIP/CPE sensor had a better signal response compared to the non-imprinted polymer-modified electrode (mag-NIP/CPE). The sensor showed a linear range from 2.5 to 57 μmol L−1 of amoxicillin (r2 = 0.9964), with a limit of detection and a limit of quantification of 0.75 and 2.48 μmol L−1, respectively. No significant interference in the electrochemical signal of amoxicillin was observed during the testing experiments in real samples (skimmed milk and river water). The proposed mag-MIP/CPE sensor could be used as a good alternative method to confront other techniques to determine amoxicillin in different samples.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFondo Nacional de Desarrollo Científico y Tecnológico-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionLaboratory of Physical Chemistry Research Faculty of Sciences National University of Engineering-
Descrição: dc.descriptionAnalytical Department Chemistry Institute State University of São Paulo (UNESP)-
Descrição: dc.descriptionNational Institute for Alternative Technologies of Detection Toxicological Evaluation Removal of Micropollutants and Radioactives (INCT-DATREM)-
Descrição: dc.descriptionAnalytical Department Chemistry Institute State University of São Paulo (UNESP)-
Descrição: dc.descriptionFAPESP: 2019/00677-7-
Descrição: dc.descriptionCNPq: 301728/2019-4-
Descrição: dc.descriptionCNPq: 408050/2018-7-
Descrição: dc.descriptionCNPq: 465571/2014-0-
Idioma: dc.languageen-
Relação: dc.relationFrontiers in Chemistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectamoxicillin-
Palavras-chave: dc.subjectcarbon paste electrode-
Palavras-chave: dc.subjectelectrochemical sensor-
Palavras-chave: dc.subjectmag-MIP-
Palavras-chave: dc.subjectselective adsorption-
Título: dc.titleDevelopment of a New Electrochemical Sensor Based on Mag-MIP Selective Toward Amoxicillin in Different Samples-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.