Nanosystem functionalization strategies for prostate cancer treatment: a review

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorde Araújo, Jennifer Thayanne Cavalcante [UNESP]-
Autor(es): dc.creatorDuarte, Jonatas Lobato [UNESP]-
Autor(es): dc.creatorDi Filippo, Leonardo Delello [UNESP]-
Autor(es): dc.creatorAraújo, Victor Hugo Sousa [UNESP]-
Autor(es): dc.creatorCarvalho, Gabriela Corrêa [UNESP]-
Autor(es): dc.creatorChorilli, Marlus [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:53:30Z-
Data de disponibilização: dc.date.available2022-02-22T00:53:30Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/1061186X.2021.1892121-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208475-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208475-
Descrição: dc.descriptionProstate cancer (PC) has a high morbidity and mortality rate worldwide, and the current clinical guidelines can vary depending on the stage of the disease. Drug delivery nanosystems (DDNs) can improve biopharmaceutical properties of encapsulated anti-cancer drugs by modulating their release kinetics, improving physicochemical stability and reducing toxicity. DDN can also enhance the ability of specific targeting through surface modification by coupling ligands (antibodies, nucleic acids, peptides, aptamer, proteins), thus favouring the cell internalisation process by endocytosis. The purposes of this review are to describe the limitations in the treatment of PC, explore different functionalization such as polymeric, lipid and inorganic nanosystems aimed at the treatment of PC, and demonstrate the improvement of this modification for an active target, as alternative and promising candidates for new therapies.-
Descrição: dc.descriptionDepartment of Drugs and Pharmaceutics School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Drugs and Pharmaceutics School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationJournal of Drug Targeting-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectactive target-
Palavras-chave: dc.subjectCancer therapy-
Palavras-chave: dc.subjectdrug delivery system-
Palavras-chave: dc.subjectligand-specific-
Palavras-chave: dc.subjectprostate cancer-
Título: dc.titleNanosystem functionalization strategies for prostate cancer treatment: a review-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.