Sericin based nanoformulations: a comprehensive review on molecular mechanisms of interaction with organisms to biological applications

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorDongguk University-Seoul-
Autor(es): dc.contributorFederal University of ABC. Av. Dos Estados-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidad Nacional Autonoma de Mexico-
Autor(es): dc.contributorSustainability of Natural Resources and Energy Programs-
Autor(es): dc.creatorDas, Gitishree-
Autor(es): dc.creatorShin, Han-Seung-
Autor(es): dc.creatorCampos, Estefânia V. Ramos-
Autor(es): dc.creatorFraceto, Leonardo Fernandes [UNESP]-
Autor(es): dc.creatordel Pilar Rodriguez-Torres, Maria-
Autor(es): dc.creatorMariano, Kelli Cristina Freitas-
Autor(es): dc.creatorde Araujo, Daniele Ribeiro-
Autor(es): dc.creatorFernández-Luqueño, Fabián-
Autor(es): dc.creatorGrillo, Renato [UNESP]-
Autor(es): dc.creatorPatra, Jayanta Kumar-
Data de aceite: dc.date.accessioned2022-02-22T00:53:09Z-
Data de disponibilização: dc.date.available2022-02-22T00:53:09Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1186/s12951-021-00774-y-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208342-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208342-
Descrição: dc.descriptionBackground: The advances in products based on nanotechnology have directed extensive research on low-cost, biologically compatible, and easily degradable materials. Main body: Sericin (SER) is a protein mainly composed of glycine, serine, aspartic acid, and threonine amino acids removed from the silkworm cocoon (particularly Bombyx mori and other species). SER is a biocompatible material with economic viability, which can be easily functionalized due to its potential crosslink reactions. Also, SER has inherent biological properties, which makes possible its use as a component of pharmaceutical formulations with several biomedical applications, such as anti-tumor, antimicrobials, antioxidants and as scaffolds for tissue repair as well as participating in molecular mechanisms attributed to the regulation of transcription factors, reduction of inflammatory signaling molecules, stimulation of apoptosis, migration, and proliferation of mesenchymal cells. Conclusion: In this review, the recent innovations on SER-based nano-medicines (nanoparticles, micelles, films, hydrogels, and their hybrid systems) and their contributions for non-conventional therapies are discussed considering different molecular mechanisms for promoting their therapeutic applications.[Figure not available: see fulltext.]-
Descrição: dc.descriptionNational Research Foundation of Korea-
Descrição: dc.descriptionResearch Institute of Biotechnology & Medical Converged Science Dongguk University-Seoul-
Descrição: dc.descriptionDepartment of Food Science & Biotechnology Dongguk University-Seoul-
Descrição: dc.descriptionHuman and Natural Sciences Center Federal University of ABC. Av. Dos Estados, 5001. Bl. A, T3, Lab. 503-3. Bangú-
Descrição: dc.descriptionInstitute of Science and Technology of Sorocaba São Paulo State University (UNESP), Av. Três de março, 511, Alto da Boa Vista-
Descrição: dc.descriptionDepartamento de Ingenieria Molecular de Materiales Centro de Fisica Aplicada y Tecnologia Avanzada Universidad Nacional Autonoma de Mexico, Blvd. Juriquilla 3001-
Descrição: dc.descriptionSustainability of Natural Resources and Energy Programs, Cinvestav-Saltillo-
Descrição: dc.descriptionDepartment of Physics and Chemistry São Paulo State University (UNESP), Avenida Brasil, 56, Centro-
Descrição: dc.descriptionInstitute of Science and Technology of Sorocaba São Paulo State University (UNESP), Av. Três de março, 511, Alto da Boa Vista-
Descrição: dc.descriptionDepartment of Physics and Chemistry São Paulo State University (UNESP), Avenida Brasil, 56, Centro-
Descrição: dc.descriptionNational Research Foundation of Korea: 2020R1G1A1004667-
Idioma: dc.languageen-
Relação: dc.relationJournal of Nanobiotechnology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiomaterials-
Palavras-chave: dc.subjectBiomedical-
Palavras-chave: dc.subjectDrug delivery-
Palavras-chave: dc.subjectNanoformulation-
Palavras-chave: dc.subjectSericin-
Palavras-chave: dc.subjectSilk protein-
Título: dc.titleSericin based nanoformulations: a comprehensive review on molecular mechanisms of interaction with organisms to biological applications-
Aparece nas coleções:Repositório Institucional - Unesp

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