Identification of novel mRNA isoforms associated with meat tenderness using RNA sequencing data in beef cattle

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversity of Guelph-
Autor(es): dc.contributorNational Council for Scientific and Technological Development (CNPq)-
Autor(es): dc.creatorMuniz, Maria Malane Magalhães [UNESP]-
Autor(es): dc.creatorFonseca, Larissa Fernanda Simielli [UNESP]-
Autor(es): dc.creatordos Santos Silva, Danielly Beraldo [UNESP]-
Autor(es): dc.creatorde Oliveira, Hinayah Rojas-
Autor(es): dc.creatorBaldi, Fernando [UNESP]-
Autor(es): dc.creatorChardulo, Artur Loyola [UNESP]-
Autor(es): dc.creatorFerro, Jesus Aparecido [UNESP]-
Autor(es): dc.creatorCánovas, Angela-
Autor(es): dc.creatorde Albuquerque, Lucia Galvão [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:52:59Z-
Data de disponibilização: dc.date.available2022-02-22T00:52:59Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.meatsci.2020.108378-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208282-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208282-
Descrição: dc.descriptionThe Warner-Bratzler shear force (WBSF) and myofibrillar fragmentation index (MFI) are complementary methodologies used to measure beef tenderness. Longissimus thoracis samples from the 20 most extreme bulls (out of 80 bulls set) for WBSF (tender (n = 10) and tough (n = 10)) and MFI (high (n = 10) and low (n = 10)) traits were collected to perform transcriptomic analysis using RNA-Sequencing. All analysis were performed through CLC Genomics Workbench. A total of 39 and 27 transcripts for WBSF and MFI phenotypes were DE, respectively. The possible DE novel mRNA isoforms, for WBSF and MFI traits, are myosin encoders (e.g. MYL1 and MYL6). In addition, we identified potential mRNA isoforms related to genes affecting the speed fibers degradation during the meat aging process. The DE novel transcripts are transcripted by genes with biological functions related to oxidative process, energy production and striated muscle contraction. The results suggest that the identified mRNA isoforms could be used as potential candidate to select animals in order to improve meat tenderness.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionSchool of Agricultural and Veterinarian Sciences São Paulo State University (Unesp)-
Descrição: dc.descriptionCentre for Genetic Improvement of Livestock Department of Animal Biosciences University of Guelph-
Descrição: dc.descriptionNational Council for Scientific and Technological Development (CNPq)-
Descrição: dc.descriptionSão Paulo State University (Unesp) College of Veterinary and Animal Science-
Descrição: dc.descriptionSchool of Agricultural and Veterinarian Sciences São Paulo State University (Unesp)-
Descrição: dc.descriptionSão Paulo State University (Unesp) College of Veterinary and Animal Science-
Descrição: dc.descriptionCAPES: 001.-
Descrição: dc.descriptionFAPESP: 11/21241-0-
Descrição: dc.descriptionFAPESP: 2009/16118-5-
Descrição: dc.descriptionFAPESP: 2017/02470-3-
Descrição: dc.descriptionFAPESP: 2017/10630-2-
Descrição: dc.descriptionFAPESP: 2018/11154-2-
Descrição: dc.descriptionFAPESP: 2018/20026-8-
Idioma: dc.languageen-
Relação: dc.relationMeat Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectMeat maturation-
Palavras-chave: dc.subjectMFI-
Palavras-chave: dc.subjectNovel transcripts-
Palavras-chave: dc.subjectRNA-Seq-
Palavras-chave: dc.subjectWBSF-
Título: dc.titleIdentification of novel mRNA isoforms associated with meat tenderness using RNA sequencing data in beef cattle-
Aparece nas coleções:Repositório Institucional - Unesp

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