Characteristics, Properties and Analytical/Bioanalytical Methods of 5-Aminosalicylic Acid: A Review

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorTavares Junior, Alberto Gomes [UNESP]-
Autor(es): dc.creatorde Araújo, Jennifer Thayanne Cavalcante [UNESP]-
Autor(es): dc.creatorMeneguin, Andréia Bagliotti [UNESP]-
Autor(es): dc.creatorChorilli, Marlus [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:52:43Z-
Data de disponibilização: dc.date.available2022-02-22T00:52:43Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/10408347.2020.1848516-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208206-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208206-
Descrição: dc.descriptionFive-aminosalicylic acid (5-ASA) is an anti-inflammatory drug indicated in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Among the analytical methods of quantification of 5-ASA described in the literature, the High Efficiency Liquid Chromatography stands out, a sensitive technique but with a high cost. In recent years, alternative methods have been developed, presenting efficiency and reduced cost, such as UV/visible spectrophotometric, spectrofluorescent, and electrochemical methods, techniques recommended for the application in quality control and quantification of 5-ASA in pharmaceutical forms and biological fluids. This article aims to review the physicochemical characteristics, pharmacokinetics, mechanisms of action, controlled release systems, and the different analytical and bioanalytical methods for the quantification of 5-ASA.-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionSchool of Pharmaceutical Sciences São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationCritical Reviews in Analytical Chemistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subject5-ASA-
Palavras-chave: dc.subjectAnalytical methods-
Palavras-chave: dc.subjectdrug delivery systems-
Palavras-chave: dc.subjectmechanisms of action-
Palavras-chave: dc.subjectphysicochemical characteristics-
Título: dc.titleCharacteristics, Properties and Analytical/Bioanalytical Methods of 5-Aminosalicylic Acid: A Review-
Aparece nas coleções:Repositório Institucional - Unesp

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