Improving enzyme production by solid-state cultivation in packed-bed bioreactors by changing bed porosity and airflow distribution

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.creatorPerez, Caroline Lopes [UNESP]-
Autor(es): dc.creatorCasciatori, Fernanda Perpétua-
Autor(es): dc.creatorThoméo, João Cláudio [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:52:35Z-
Data de disponibilização: dc.date.available2022-02-22T00:52:35Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s00449-020-02466-7-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208164-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208164-
Descrição: dc.descriptionEnzymes production by solid-state cultivation in packed-bed bioreactor needs to be improved by mathematical modeling and also by experimentation. In this work, a mixture of sugarcane bagasse and wheat bran was used for the growth of the fungus Myceliophthora thermophila I-1D3b, able to secrete endoglucanase and xylanase, enzymes of interest in the second-generation ethanol production. Bench and pilot-scale bioreactors were used for the experiments, while critical parameters as bed porosity and airflow distribution were evaluated. Results showed enzymes with higher activities for the most porous medium, even though the less substrate amount to be cultivated. For the pilot-scale bioreactor, only the most porous medium was evaluated using different airflow distribution techniques. Using an inner tube for air supply resulted in more homogeneous enzyme production, with higher activities. The results here presented will be helpful for the scale-up of this class of bioreactor into industrial apparatuses.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionFood Engineering and Technology Department Institute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP), Cristóvão Colombo, 2265, Jardim Nazareth-
Descrição: dc.descriptionGraduate Program of Chemical Engineering Federal University of São Carlos (UFSCar), Rod. Washington Luiz km 235, SP-310-
Descrição: dc.descriptionFood Engineering and Technology Department Institute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP), Cristóvão Colombo, 2265, Jardim Nazareth-
Descrição: dc.descriptionCNPq: 132957/2016-7-
Descrição: dc.descriptionFAPESP: 2014/23453-3-
Descrição: dc.descriptionFAPESP: 2018/00996-2-
Descrição: dc.descriptionCNPq: 430786/2018-2-
Formato: dc.format537-548-
Idioma: dc.languageen-
Relação: dc.relationBioprocess and Biosystems Engineering-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCellulase-
Palavras-chave: dc.subjectFixed bioreactor-
Palavras-chave: dc.subjectPacking density-
Palavras-chave: dc.subjectScale-up-
Palavras-chave: dc.subjectSolid-state fermentation-
Título: dc.titleImproving enzyme production by solid-state cultivation in packed-bed bioreactors by changing bed porosity and airflow distribution-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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