Chitosan enhances the antimicrobial photodynamic inactivation mediated by Photoditazine® against Streptococcus mutans

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade do Vale do Paraíba/UNIVAP-
Autor(es): dc.contributorCeará Federal University-
Autor(es): dc.creatorde Souza, Cheyenne Marçal [UNESP]-
Autor(es): dc.creatorGarcia, Maíra Terra [UNESP]-
Autor(es): dc.creatorde Barros, Patrícia Pimentel [UNESP]-
Autor(es): dc.creatorPedroso, Lara Luise Castro [UNESP]-
Autor(es): dc.creatorWard, Rafael Araújo da Costa [UNESP]-
Autor(es): dc.creatorStrixino, Juliana Ferreira-
Autor(es): dc.creatorMelo, Vânia Maria Maciel-
Autor(es): dc.creatorJunqueira, Juliana Campos [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:52:11Z-
Data de disponibilização: dc.date.available2022-02-22T00:52:11Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.pdpdt.2020.102001-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/208020-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/208020-
Descrição: dc.descriptionChitosan (CS), a biopolymer with intrinsic antimicrobial activity, can increase antimicrobial photodynamic inactivation (aPDI). The aim of this study was to evaluate the capacity of CS to potentiate the efficacy of Photoditazine® (PDZ)-mediated aPDI of the cariogenic bacterium Streptococcus mutans. CS effectively augmented the effects of aPDI, with reductions of approximately 4.5 logs in both planktonic and biofilm states. The combined treatment was also capable of reducing the number of S. mutans cells and amount of extracellular matrix in biofilms formed on enamel surfaces, which were characterized using scanning electron microscopy analysis. Furthermore, CS increased the absorption of PDZ by S. mutans cells. The combination of CS with PDZ-mediated aPDI is hence a promising antimicrobial approach against S. mutans and may be useful to control dental caries.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis Institute of Science and Technology São Paulo State University/UNESP-
Descrição: dc.descriptionFotobiologia Aplicada à Saúde (FOTOBIOS) Instituto de Pesquisa e Desenvolvimento (IP&D) Universidade do Vale do Paraíba/UNIVAP-
Descrição: dc.descriptionDepartment of Biology Laboratory of Microbial Ecology and Biotechnology Pici Ceará Federal University-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis Institute of Science and Technology São Paulo State University/UNESP-
Idioma: dc.languageen-
Relação: dc.relationPhotodiagnosis and Photodynamic Therapy-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAntimicrobial photodynamic inactivation-
Palavras-chave: dc.subjectChitosan-
Palavras-chave: dc.subjectPhotoditazine®-
Palavras-chave: dc.subjectStreptococcus mutans-
Título: dc.titleChitosan enhances the antimicrobial photodynamic inactivation mediated by Photoditazine® against Streptococcus mutans-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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