Atenção: Todas as denúncias são sigilosas e sua identidade será preservada.
Os campos nome e e-mail são de preenchimento opcional
Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual de Campinas (UNICAMP) | - |
Autor(es): dc.contributor | Queen's University Belfast | - |
Autor(es): dc.contributor | University at Campinas | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.creator | Salles, Tais Helena Costa | - |
Autor(es): dc.creator | Volpe-Zanutto, Fabiana | - |
Autor(es): dc.creator | De Oliveira Sousa, Ilza Maria | - |
Autor(es): dc.creator | MacHado, Daisy | - |
Autor(es): dc.creator | Zanatta, Ana Caroline [UNESP] | - |
Autor(es): dc.creator | Vilegas, Wagner [UNESP] | - |
Autor(es): dc.creator | Lancellotti, Marcelo | - |
Autor(es): dc.creator | Foglio, Mary Ann | - |
Autor(es): dc.creator | D'Avila, Marcos Akira | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:52:04Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:52:04Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2020-10-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1088/1748-605X/ab9bb1 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/207982 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/207982 | - |
Descrição: dc.description | The guided tissue regeneration (GTR) technique can be applied in dentistry and other medical specializations, such as orthopedics. In modern dentistry, GTR has been used in periodontics and implantology to treat periodontal defects, to reconstruct lost, damaged and atrophied bone tissue in dental implant procedures, and to preserve alveolar bases after tooth extraction. In order to create and improve new therapies and to develop new biomaterials that restore, improve and prevent aggravation of compromised tissue function, poly (ϵ-caprolactone) (PCL) polymer membranes were obtained by the electrospinning process and were associated with two plant extracts: Pterodon pubescens Benth (P. pubescens) and Arrabidaea chica Verlot (A. chica) which are characterized by their pharmacological activities of anti-inflammatory and healing actions, respectively. Fiber morphology was analyzed using scanning electron microscopy (SEM), where fiber average diameter was measured from SEM images. Contact angle measurements were performed in order to evaluate the hydrophilicity of electrospun membranes containing vegetal extract. High-performance liquid chromatography was used to evaluate the ability to release active ingredients. Cytotoxicity and cell proliferation assays were performed in vitro on NIH-3T3 cells for 1, 3 and 7 d. Electrospun PCL membranes associated with plant extracts P. pubescens and/or A. chica presented a controlled release profile of the active compounds induced fibroblast formation, suggesting that they are promising and suitable for applications in GTR. | - |
Descrição: dc.description | Department of Manufacturing and Materials Engineering School of Mechanical Engineering University of Campinas UNICAMP | - |
Descrição: dc.description | School of Pharmacy Queen's University Belfast | - |
Descrição: dc.description | Graduate School of Bioscience and Technology of Bioactive Products Biology Institute University at Campinas | - |
Descrição: dc.description | Faculdade de Ciências Médicas Universidade Estadual de Campinas UNICAMP | - |
Descrição: dc.description | Faculty of Pharmaceutical Science University at Campinas | - |
Descrição: dc.description | Instituto de Biociencias Univ Estadual Paulista UNESP | - |
Descrição: dc.description | Instituto de Biociencias Univ Estadual Paulista UNESP | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Biomedical Materials (Bristol) | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Arrabidaea chica | - |
Palavras-chave: dc.subject | Guided tissue regeneration | - |
Palavras-chave: dc.subject | Poly (ϵ-caprolactone) | - |
Palavras-chave: dc.subject | Pterodon pubescens | - |
Título: dc.title | Electrospun PCL-based nanofibers Arrabidaea chica Verlot - Pterodon pubescens Benth loaded: Synergic effect in fibroblast formation | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
O Portal eduCAPES é oferecido ao usuário, condicionado à aceitação dos termos, condições e avisos contidos aqui e sem modificações. A CAPES poderá modificar o conteúdo ou formato deste site ou acabar com a sua operação ou suas ferramentas a seu critério único e sem aviso prévio. Ao acessar este portal, você, usuário pessoa física ou jurídica, se declara compreender e aceitar as condições aqui estabelecidas, da seguinte forma: