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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade de São Paulo (USP) | - |
Autor(es): dc.contributor | Universidade Federal de São Paulo (UNIFESP) | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Justus-Liebig-University Giessen | - |
Autor(es): dc.creator | Batatinha, Helena | - |
Autor(es): dc.creator | Tavares-Silva, Edgar | - |
Autor(es): dc.creator | Leite, Geovana S. F. | - |
Autor(es): dc.creator | Resende, Ayane S. | - |
Autor(es): dc.creator | Albuquerque, José A. T. | - |
Autor(es): dc.creator | Arslanian, Christina | - |
Autor(es): dc.creator | Fock, Ricardo A. | - |
Autor(es): dc.creator | Lancha, Antônio H. | - |
Autor(es): dc.creator | Lira, Fabio S. [UNESP] | - |
Autor(es): dc.creator | Krüger, Karsten | - |
Autor(es): dc.creator | Thomatieli-Santos, Ronaldo | - |
Autor(es): dc.creator | Rosa-Neto, José C. | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:51:43Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:51:43Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2020-11-30 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1038/s41598-020-75464-0 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/207889 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/207889 | - |
Descrição: dc.description | Probiotic supplementation arises as playing an immune-stimulatory role. High-intensity and -volume exercise can inhibit immune cell function, which threatens athletic performance and recovery. We hypothesized that 30 days of probiotic supplementation could stabilize the immune system of athletes preventing immune suppression after a marathon race. Twenty-seven male marathonists were double-blinded randomly into probiotic (Bifidobacterium-animalis-subsp.-Lactis (10 × 109) and Lactobacillus-Acidophilus (10 × 109) + 5 g of maltodextrin) and placebo (5 g of maltodextrin) group. They received 30 sachets and supplemented 1 portion/day during 30 days before the race. Blood were collected 30 days before (rest), 1 day before (pre), 1 h after (post) and 5 days after the race (recovery). Both chronic and acute exercise modulated a different T lymphocyte population (CD3+CD4−CD8− T-cells), increasing pre-race, decreasing post and returning to rest values at the recovery. The total number of CD8 T cell and the memory subsets statistically decreased only in the placebo group post-race. Pro-inflammatory cytokine production by stimulated lymphocytes decreased in the probiotic group after the supplementation period. 30 days of probiotic supplementation maintained CD8 T cell and effector memory cell population and played an immunomodulatory role in stimulated lymphocytes. Both, training and marathon modulated a non-classical lymphocyte population regardless of probiotic supplementation. | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | Immunometabolism Research Group Institute of Biomedical Sciences University of São Paulo (USP) | - |
Descrição: dc.description | Programa de pós-graduação em psicobiologia Universidade Federal de São Paulo | - |
Descrição: dc.description | Laboratory of Applied Nutrition and Metabolism School of Physical Education and Sports University of São Paulo | - |
Descrição: dc.description | Department of Immunology Institute of Biomedical Sciences University of São Paulo | - |
Descrição: dc.description | Department of Clinical and Toxicological Analysis School of Pharmaceutical Sciences University of São Paulo | - |
Descrição: dc.description | Exercise and Immunometabolism Research Group Post-Graduation Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP) School of Technology and Sciences | - |
Descrição: dc.description | Department of Exercise Physiology and Sports Therapy Justus-Liebig-University Giessen | - |
Descrição: dc.description | Department of Bioscience Universidade Federal de São Paulo | - |
Descrição: dc.description | Department of Cell and Developmental Biology University of São Paulo, 1524, Prof Lineu Prestes Av. | - |
Descrição: dc.description | Exercise and Immunometabolism Research Group Post-Graduation Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP) School of Technology and Sciences | - |
Descrição: dc.description | FAPESP: 2016/10561-8 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Scientific Reports | - |
???dc.source???: dc.source | Scopus | - |
Título: dc.title | Probiotic supplementation in marathonists and its impact on lymphocyte population and function after a marathon: a randomized placebo-controlled double-blind study | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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